Evidence map›Paper›PMID 34429489›Full record

ArticleScientific reports2021

CD8

Yan-Long Ren, Tao-Tao Li, Wei Cui, Li-Min Zhao, Na Gao, Hua Liao, Jiang-Hui Zhang, Jun-Ming Zhu, Zhi-Yu Qiao, Shi-Chao Guo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Investigation of the causal effect and molecular signatures of serum hydroxyvitamin D on atherosclerosis: a Mendelian randomization and transcriptomic approach.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Article
  4. Review
  5. Article
  6. Evaluation of a multi-epitope vaccine PME forFrontiers in immunology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yan-Long Ren *Department of Cardiology, Beijing Lab for Cardiovascular Precision Medicine, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing, China.
Tao-Tao Li *Department of Rheumatology, Capital Medical University Affiliated Anzhen Hospital, 2 Anzhen Road, Chaoyang District, Beijing, China.
Wei CuiDepartment of Rheumatology, Capital Medical University Affiliated Anzhen Hospital, 2 Anzhen Road, Chaoyang District, Beijing, China.
Li-Min ZhaoDepartment of Rheumatology, Capital Medical University Affiliated Anzhen Hospital, 2 Anzhen Road, Chaoyang District, Beijing, China.
Na GaoDepartment of Rheumatology, Capital Medical University Affiliated Anzhen Hospital, 2 Anzhen Road, Chaoyang District, Beijing, China.
Hua LiaoDepartment of Rheumatology, Capital Medical University Affiliated Anzhen Hospital, 2 Anzhen Road, Chaoyang District, Beijing, China.
Jiang-Hui ZhangDepartment of Rheumatology, Capital Medical University Affiliated Anzhen Hospital, 2 Anzhen Road, Chaoyang District, Beijing, China.
Jun-Ming ZhuDepartment of Cardiovascular Surgery, Capital Medical University Affiliated Anzhen Hospital, Beijing, China.
Zhi-Yu QiaoDepartment of Cardiovascular Surgery, Capital Medical University Affiliated Anzhen Hospital, Beijing, China.
Shi-Chao GuoDepartment of Cardiovascular Surgery, Capital Medical University Affiliated Anzhen Hospital, Beijing, China.
Li-Li PanDepartment of Rheumatology, Capital Medical University Affiliated Anzhen Hospital, 2 Anzhen Road, Chaoyang District, Beijing, China. lilypansxmu@sina.com.
Capital Medical University · CNBeijing Anzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon-gamma (IFN-γ) is a cytokine involved in the pathogenesis of Takayasu's arteritis (TAK). However, the source of IFN-γ in TAK patients is not fully clear. We aimed to investigate the source of IFN-γ in TAK. 60 TAK patients and 35 health controls were enrolled. The lymphocyte subsets of peripheral blood were detected by flow cytometry, cytokines were detected by Bio-plex. The correlation among lymphocyte subsets, cytokines and disease activity indexes was analyzed by person correlation. The level of serum IFN-γ in TAK patients was significantly increased (P < 0.05). The percentage of CD3

Indexed as

AdultCD8-Positive T-LymphocytesCells, CulturedFemaleHumansInterferon-gammaMaleMiddle AgedTakayasu ArteritisInterferon-gamma

Identifiers

PMID34429489
PMCPMC8384861
OpenAlexW3195313040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.