Evidence map›Paper›PMID 34429467›Full record

ArticleScientific reports2021

3D printing fluorescent material with tunable optical properties.

Alberto J Ruiz, Sadhya Garg, Samuel S Streeter, Mia K Giallorenzi, Ethan P M LaRochelle, Kimberley S Samkoe, Brian W Pogue

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alberto J RuizThayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA. albertojruiz.ar@gmail.com.
Sadhya GargThayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Samuel S StreeterThayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Mia K GiallorenziThayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Ethan P M LaRochelleQUEL Imaging LLC, 85 N Main Streeet, White River Junction, VT, 05001, USA.
Kimberley S SamkoeThayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Brian W PogueThayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, NH, 03755, USA.
Dartmouth College · USWhite River Junction VA Medical Center · US

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Bryan Quilty Spring · 2001 to 2026
$27.9M
Fluorescence Guided Surgery Standardization ToolsR43EB029804 · NIBIB · QUEL IMAGING LLC · PI LAROCHELLE, ETHAN PHILLIP MARSHALL · 2020 to 2020
$266k
NCI NIH HHS P01 CA084203NIBIB NIH HHS R43 EB029804
6 · The paper itself

Abstract

The 3D printing of fluorescent materials could help develop, validate, and translate imaging technologies, including systems for fluorescence-guided surgery. Despite advances in 3D printing techniques for optical targets, no comprehensive method has been demonstrated for the simultaneous incorporation of fluorophores and fine-tuning of absorption and scattering properties. Here, we introduce a photopolymer-based 3D printing method for manufacturing fluorescent material with tunable optical properties. The results demonstrate the ability to 3D print various individual fluorophores at reasonably high fluorescence yields, including IR-125, quantum dots, methylene blue, and rhodamine 590. Furthermore, tuning of the absorption and reduced scattering coefficients is demonstrated within the relevant mamalian soft tissue coefficient ranges of 0.005-0.05 mm

Indexed as

Absorption, RadiationAcrylic ResinsFluorescenceFluorescent DyesPrinting, Three-DimensionalAcrylic ResinsFluorescent Dyes

Identifiers

PMID34429467
PMCPMC8384872
OpenAlexW3194098726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.