Evidence map›Paper›PMID 34429416›Full record

ArticleNature communications2021

Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC.

Jakob M Silberberg, Robin A Corey, Lisa Hielkema, Charlott Stock, Phillip J Stansfeld, Cristina Paulino, Inga Hänelt

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Lipids are essential for potassium transport by KdpFABC from E. coli.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Conduction pathway for potassium through the E. coli pump KdpFABC.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
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  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Jakob M Silberberg *Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt/Main, Germany.ORCID http://orcid.org/0000-0003-1721-8666
Robin A Corey *Department of Biochemistry, University of Oxford, Oxford, UK.
Lisa Hielkema *Department of Structural Biology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-8328-5176
Charlott StockInstitute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt/Main, Germany.ORCID http://orcid.org/0000-0001-5471-3696
Phillip J StansfeldSchool of Life Sciences & Department of Chemistry, University of Warwick, Coventry, UK. phillip.stansfeld@warwick.ac.uk.ORCID http://orcid.org/0000-0001-8800-7669
Cristina PaulinoDepartment of Structural Biology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands. c.paulino@rug.nl.ORCID http://orcid.org/0000-0001-7017-109X
Inga HäneltInstitute of Biochemistry, Biocenter, Goethe University Frankfurt, Frankfurt/Main, Germany. haenelt@biochem.uni-frankfurt.de.ORCID http://orcid.org/0000-0003-1495-3163
Goethe University Frankfurt · DEBiotechnology Institute · USUniversity of Groningen · NLUniversity of Oxford · GBUniversity of Warwick · GB

Funding

Biotechnology and Biological Sciences Research Council BB/P01948X/1Biotechnology and Biological Sciences Research Council BB/R002517/1Biotechnology and Biological Sciences Research Council BB/S003339/1Medical Research Council MR/S009213/1Wellcome TrustWellcome Trust 208361/Z/17/Z
6 · The paper itself

Abstract

KdpFABC, a high-affinity K

Indexed as

Adenosine TriphosphatasesAspartic AcidBinding SitesCation Transport ProteinsCryoelectron MicroscopyEscherichia coliEscherichia coli ProteinsIon TransportLysineMolecular Dynamics SimulationMutationPhenylalaninePotassiumProtein SubunitsSodium-Potassium-Exchanging ATPaseAdenosine TriphosphatasesAspartic AcidCation Transport ProteinsEscherichia coli ProteinsLysinePhenylalaninePotassiumpotassium translocating Kdp-ATPase, E coliProtein SubunitsSodium-Potassium-Exchanging ATPase

Identifiers

PMID34429416
PMCPMC8385062
OpenAlexW3195822029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.