Evidence map›Paper›PMID 34429366›Full record

ArticleNeurology(R) neuroimmunology & neuroinflammation2021

Melanoma Cell Adhesion Molecule Expressing Helper T Cells in CNS Inflammatory Demyelinating Diseases.

Ryotaro Ikeguchi, Yuko Shimizu, Akihiro Kondo, Natsuki Kanda, Hayato So, Haruka Kojima, Kazuo Kitagawa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology(R) neuroimmunology & neuroinflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ryotaro IkeguchiFrom the Department of Neurology, Tokyo Women's Medical University, Japan.
Yuko ShimizuFrom the Department of Neurology, Tokyo Women's Medical University, Japan. shimizu.yuko@twmu.ac.jp.
Akihiro KondoFrom the Department of Neurology, Tokyo Women's Medical University, Japan.
Natsuki KandaFrom the Department of Neurology, Tokyo Women's Medical University, Japan.
Hayato SoFrom the Department of Neurology, Tokyo Women's Medical University, Japan.
Haruka KojimaFrom the Department of Neurology, Tokyo Women's Medical University, Japan.
Kazuo KitagawaFrom the Department of Neurology, Tokyo Women's Medical University, Japan.
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo elucidate the relationship between melanoma cell adhesion molecule (MCAM)-expressing lymphocytes and pathogenesis of CNS inflammatory demyelinating diseases (IDDs).

methodsPatients with multiple sclerosis (MS) (n = 72) and neuromyelitis optica spectrum disorder (NMOSD, n = 29) were included. We analyzed the frequency and absolute numbers of MCAM

resultsThe frequency of MCAM DISCUSSION: MCAM

Indexed as

Multiple SclerosisNeuromyelitis OpticaAdultAgedCD146 AntigenFemaleHumansMaleMiddle AgedMultiple Sclerosis, Relapsing-RemittingMyasthenia GravisT-Lymphocytes, Helper-InducerYoung AdultCD146 AntigenMCAM protein, human

Identifiers

PMID34429366
PMCPMC8387012
OpenAlexW3194420947

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.