ArticleBMJ open2021
Use of targeted mobile X-ray screening and computer-aided detection software to identify tuberculosis among high-risk groups in Romania: descriptive results of the E-DETECT TB active case-finding project.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 18 citations in OpenAlex.
- The performance of computer-aided detection for chest radiography in tuberculosis screening: a population-based retrospective cohort study.Emerging microbes & infections · 2025Article
- AI-Powered Chest X-Ray for Diagnosing Pulmonary Tuberculosis in County and Township Health Care Facilities in Yichang: Retrospective, Real-World Study.Journal of medical Internet research · 2025Article
- Performance of Computer-Aided Detection Software in Tuberculosis Case Finding in Township Health Centers in China.Chronic diseases and translational medicine · 2025Article
- Artificial intelligence: a useful tool in active tuberculosis screening among vulnerable groups in Romania - advantages and limitations.Frontiers in public health · 2025Article
- Impact of vitamin C deficiency on imaging patterns and ventilatory function in pulmonary tuberculosis.Frontiers in medicine · 2025Article
- From pandemic to endemic: assessing the impact of COVID-19 history and socio-demographic factors on quality of life in tuberculosis patients.Frontiers in medicine · 2025Article
- Article
- Early detection of tuberculosis: a systematic review.Pneumonia (Nathan Qld.) · 2024Review
- Navigating the Maze: Exploring Non-Oncological Complexities in Non-Small-Cell Lung Cancer.Cancers · 2024Article
- Pathogenesis, Prophylaxis, and Treatment ofBiomedicines · 2024Review
- Applicability of artificial intelligence-based computer-aided detection (AI-CAD) for pulmonary tuberculosis to community-based active case finding.Tropical medicine and health · 2024Article
- The rise of artificial intelligence reading of chest X-rays for enhanced TB diagnosis and elimination.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023Article
- The Bidirectional Relationship between Pulmonary Tuberculosis and Lung Cancer.International journal of environmental research and public health · 2023Review
- Evaluation of chest X-ray with automated interpretation algorithms for mass tuberculosis screening in prisons: a cross-sectional study.Lancet regional health. Americas · 2023Article
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Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo implement and assess the mobile X-ray unit (MXU) equipped with digital radiography, computer-aided detection (CAD) software and molecular point of care tests to improve early tuberculosis (TB) diagnosis in vulnerable populations in a TB outreach screening programme in Romania.
designDescriptive study. SETTINGS: Prisons in Bucharest and other cities in the southern part of Romania, homeless shelters and services for problem drug users in Bucharest, and Roma populations in Bucharest and Craiova.
participants5510 individuals attended the MXU service; 5003 persons were radiologically screened, 61% prisoners, 15% prison staff, 11% Roma population, 10% homeless persons and/or problem drug users and 3% other.
interventionsRadiological digital chest X-ray (CXR) screening of people at risk for TB, followed by CAD and human reading of the CXRs, and further TB diagnostics when the pulmonologist classified the CXR as suggestive for TB. PRIMARY AND SECONDARY OUTCOME MEASURES: Ten bacteriologically confirmed TB cases were identified translating into an overall yield of 200 per 100 000 persons screened (95% CIs of 109 to 368 per 100 000). Prevalence rates among homeless persons and/or problem drug users (826/100 000; 95% CI 326 to 2105/100 000) and the Roma population (345/100 000; 95% CI 95 to 1251/100 000) were particularly high.
resultsThe human reader classified 6.4% (n=317) of the CXRs as suspect for TB (of which 32 were highly suggestive for TB); 16.3% of all CXRs had a CAD4TB version 6 score >50. All 10 diagnosed TB patients had a CAD4TB score >50; 9 had a CAD4TB score >60.
conclusionsGiven the high TB prevalence rates found among homeless persons and problem drug users and in the Roma population, targeted active case finding has the potential to deliver a major contribution to TB control in Romania.
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