Evidence map›Paper›PMID 34429187›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2021

Development and Testing of a Sedation Scale for Use in Rabbits (

Juliette Raulic, Vivian Sy Leung, Grayson A Doss, Jennifer E Graham, Krista A Keller, Christoph Mans, Miranda J Sadar, Claire Vergneau-Grosset, Daniel Sj Pang

Open access · greenAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Psychometric Properties of a Behavioral Sedation Scale for Green Iguanas (Iguana iguana).Journal of the American Association for Laboratory Animal Science : JAALAS · 2026
    Article
  2. Article
  3. Effects of Human Observer Presence on Pain Assessment Using Facial Expressions in Rabbits.Journal of the American Association for Laboratory Animal Science : JAALAS · 2023
    Article
  4. Intramuscular Alfaxalone-Butorphanol-Midazolam Compared with Ketamine-Butorphanol- Midazolam in New Zealand White Rabbits.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Juliette RaulicDepartment of Clinical Sciences, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
Vivian Sy LeungDepartment of Clinical Sciences, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
Grayson A DossDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Jennifer E GrahamCummings School of Veterinary Medicine at Tufts University, N Grafton, Massachusetts.
Krista A KellerDepartment of Veterinary Clinical Medicine, University of Illinois, Urbana, Illinois.
Christoph MansDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Miranda J SadarDepartment of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado.
Claire Vergneau-GrossetDepartment of Clinical Sciences, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
Daniel Sj PangDepartment of Clinical Sciences, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada; Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada;, Email: dsjpang@ucalgary.ca.
Université de Montréal · CAUniversity of Wisconsin–Madison · USColorado State University · USTufts University · USUniversity of Calgary · CAUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In biomedical research, rabbits are commonly sedated to facilitate a variety of procedures. Developing a sedation assessment scale enables standardization of levels of sedation and comparisons of sedation protocols, and may help in predicting sedation level requirements for different procedures. The goal of this study was to develop a rabbit sedation assessment scale using a psychometric approach. We hypothesized that the sedation scale would have construct validity, good internal consistency, and reliability. In a prospective, randomized, blinded study design, 15 (8 females, 7 males) healthy 1-y-old New Zealand white rabbits received 3 intramuscular treatments: midazolam (0.5 mg/kg;

Indexed as

AnesthesiaHypnotics and SedativesAnimalsFemaleMaleMidazolamProspective StudiesRabbitsReproducibility of ResultsHypnotics and SedativesMidazolam

Identifiers

PMID34429187
PMCPMC8603372
OpenAlexW3193326213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.