Evidence map›Paper›PMID 34429117›Full record

ArticleLipids in health and disease2021

Early postpartum abnormal glucose metabolism subtype differs according to mid-trimester lipid profile in women with gestational diabetes mellitus.

Fenghua Lai, Zeting Li, Shufan Yue, Ling Pei, Huangmeng Xiao, Zhuyu Li, Yanbing Li, Haipeng Xiao, Xiaopei Cao

Abstract read
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Article in Lipids in health and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  4. Pilates exercise in pregnancy: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2025
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Fenghua Lai *Department of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China.
Zeting Li *Department of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China.
Shufan YueDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China.
Ling PeiDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China.
Huangmeng XiaoDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China.
Zhuyu LiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital, Sun Yat-sen University, 510080, Guangzhou, China.
Yanbing LiDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China.
Haipeng XiaoDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China.
Xiaopei CaoDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan 2nd Rd, 510080, Guangzhou, China. caoxp@mail.sysu.edu.cn.

Funding

National major and development projects of China 2018YFC1314100Science and Technology Foundation of Guangzhou City 201803010101Young Teacher Foundation of Sun Yat-sen University 2017001
6 · The paper itself

Abstract

backgroundIt is unknown whether early postpartum abnormal glucose metabolism (AGM) in women with previous gestational diabetes mellitus (GDM) is related to their mid-trimester lipid profile. The aim of this study was to characterize the mid-trimester lipid profile of women who experienced GDM and developed into different pathophysiologic subtypes of early postpartum AGM.

methodsA retrospective cohort study of 498 women with history of GDM was conducted. A 75-g oral glucose tolerance test (OGTT) and plasma lipid measurements were performed at 24-28 weeks of gestation and 6-12 weeks of postpartum. Insulin secretion and sensitivity were estimated using early postpartum OGTT-based indices.

resultsWomen in the mid-trimester dyslipidemia group had higher postpartum 30-min and 2-h plasma glucose, higher postpartum 2-h plasma insulin, higher postpartum triglyceride (TG), higher postpartum low density lipoprotein cholesterol (LDL-c) concentrations, lower postpartum 30-min insulinogenic index (IGI

conclusionsGDM women with abnormal mid-trimester TG and LDL-c were predisposed to early postpartum AGM. Postpartum AGM women who experienced GDM had heterogeneous mid-trimester lipid profile when classified according to their pathophysiologic subtype.

Indexed as

AdultCholesterol, LDLDiabetes, GestationalDyslipidemiasFemaleGlucoseGlucose Tolerance TestHumansInsulinInsulin ResistanceLipidsPregnancyPregnancy Trimester, SecondRetrospective StudiesTriglyceridesCholesterol, LDLGlucoseInsulinLipidsTriglyceridesGestational diabetes mellitusGlucose metabolismLipid profileMid-trimesterPostpartum

Identifiers

PMID34429117
PMCPMC8386098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.