Evidence map›Paper›PMID 34429109›Full record

ArticleEnvironmental health : a global access science source2021

Quantifying the short-term effects of air pollution on health in the presence of exposure measurement error: a simulation study of multi-pollutant model results.

Dimitris Evangelopoulos, Klea Katsouyanni, Joel Schwartz, Heather Walton

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Air Pollution and Brain Tumors in Children. A Systematic Review.Current environmental health reports · 2026
    Pooled it
  2. The effect of ambient ozone exposure on three types of diabetes: a meta-analysis.Environmental health : a global access science source · 2023
    Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Clearing the Air on Reproductive Health: Unpacking the Impact of PMPaediatric and perinatal epidemiology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Measurement error correction for ambient PMEnvironmental research · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dimitris EvangelopoulosEnvironmental Research Group, School of Public Health, Imperial College London, Michael Uren Biomedical Engineering Hub, White City Campus, Wood Lane, W12 0BZ, London, UK. d.evangelopoulos@imperial.ac.uk.ORCID 0000-0002-1071-6892
Klea KatsouyanniEnvironmental Research Group, School of Public Health, Imperial College London, Michael Uren Biomedical Engineering Hub, White City Campus, Wood Lane, W12 0BZ, London, UK.
Joel SchwartzDepartment of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Heather WaltonEnvironmental Research Group, School of Public Health, Imperial College London, Michael Uren Biomedical Engineering Hub, White City Campus, Wood Lane, W12 0BZ, London, UK.

Funding

Department of HealthMedical Research Council MR/S019669/1
6 · The paper itself

Abstract

backgroundMost epidemiological studies estimate associations without considering exposure measurement error. While some studies have estimated the impact of error in single-exposure models we aimed to quantify the effect of measurement error in multi-exposure models, specifically in time-series analysis of PM

methodsMeasurement error was defined as the difference between ambient concentrations and personal exposure from outdoor sources. Simulation inputs for error magnitude and variability were informed by the literature. Error-free exposures with their consequent health outcome and error-prone exposures of various error types (classical/Berkson) were generated. Bias was quantified as the relative difference in effect estimates of the error-free and error-prone exposures.

resultsMortality effect estimates were generally underestimated with greater bias observed when low ratios of the true exposure variance over the error variance were assumed (27.4% underestimation for NO

conclusionsOur simulation study indicated an underestimation of true independent health effects of multiple exposures due to measurement error. Using error parameter information in future epidemiological studies should provide more accurate concentration-response functions.

Indexed as

Models, TheoreticalMortalityScientific Experimental ErrorAir PollutantsAir PollutionBiasComputer SimulationEnvironmental ExposureHumansNitrogen DioxideParticulate MatterAir PollutantsNitrogen DioxideParticulate MatterAir pollutionEffect transferMeasurement errorMixture errorNO2PM2,5Simulations

Identifiers

PMID34429109
PMCPMC8385952

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.