Evidence map›Paper›PMID 34428995›Full record

ReviewCritical reviews in biochemistry and molecular biology2021

Biosynthesis and trafficking of heme

Elise D Rivett, Lim Heo, Michael Feig, Eric L Hegg

Open access · greenAbstract readReview
In one paragraph

Review in Critical reviews in biochemistry and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Archaeal hemeFrontiers in microbiology · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Diversity of CytochromeMicroorganisms · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elise D RivettDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-5118-2612
Lim HeoDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-3153-2363
Michael FeigDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0001-9380-6422
Eric L HeggDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0003-2055-5495
Michigan State University · US

Funding

Modeling and dynamics of biomolecules on cellular scalesR35GM126948 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Michael Feig · 2018 to 2026
$3.2M
Biosynthesis and Insertion of Heme A during Cytochrome c Oxidase BiogenesisR01GM101386 · NIGMS · MICHIGAN STATE UNIVERSITY · PI HEGG, ERIC L. · 2012 to 2015
$990k
NIGMS NIH HHS R01 GM101386NIGMS NIH HHS R35 GM126948
6 · The paper itself

Abstract

Aerobic respiration is a key energy-producing pathway in many prokaryotes and virtually all eukaryotes. The final step of aerobic respiration is most commonly catalyzed by heme-copper oxidases embedded in the cytoplasmic or mitochondrial membrane. The majority of these terminal oxidases contain a prenylated heme (typically heme

Indexed as

Alkyl and Aryl TransferasesAnimalsArchaeaBacteriaBacterial ProteinsElectron Transport Complex IVEukaryotaHemeHumansMolecular Dynamics SimulationProtein ConformationProtein TransportAlkyl and Aryl TransferasesBacterial ProteinsCyoE protein, BacteriaElectron Transport Complex IVHemeheme aheme OCytochrome c oxidasecytochrome c oxidase assemblyheme a synthaseheme-copper oxidasesheme o synthaseheme oxidationheme traffickingintramembrane aromatic prenyltransferase

Identifiers

PMID34428995
PMCPMC8877297
OpenAlexW3193633273

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.