Evidence map›Paper›PMID 34428688›Full record

ArticleJournal of anxiety disorders2021

Longitudinal trajectory and predictors of change in family accommodation during exposure therapy for pediatric OCD.

Ryan J Jacoby, Hannah Smilansky, Jin Shin, Monica S Wu, Brent J Small, Sabine Wilhelm, Eric A Storch, Daniel A Geller

Open access · greenAbstract read
In one paragraph

Article in Journal of anxiety disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ryan J JacobyMassachusetts General Hospital/Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: rjjacoby@mgh.harvard.edu.
Hannah SmilanskyMassachusetts General Hospital/Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: michelle.h.smilansky@vanderbilt.edu.
Jin ShinMassachusetts General Hospital/Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: jin.shin@wustl.edu.
Monica S WuUCLA Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, Los Angeles, CA, 90095, USA. Electronic address: monicawu@ucla.edu.
Brent J SmallUniversity of South Florida, 13301 Bruce B. Downs Blvd, MHC 1346, Tampa, FL, 33612, USA. Electronic address: bsmall@usf.edu.
Sabine WilhelmMassachusetts General Hospital/Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: swilhelm@mgh.harvard.edu.
Eric A StorchBaylor College of Medicine, 1977 Butler Blvd, Suite 4-400, Houston, TX, 77030, USA. Electronic address: eric.storch@bcm.edu.
Daniel A GellerMassachusetts General Hospital/Harvard Medical School, 185 Cambridge Street, Suite 2000, Boston, MA, 02114, USA. Electronic address: dan.geller@mgh.harvard.edu.
Harvard University · USBaylor College of Medicine · USUCLA Medical Center · USUniversity of South Florida · US

Funding

TRAINING THE SCIENCE OF CHILD MENTAL HEALTH TREATMENTT32MH073517 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUMA JACOB, John C. Piacentini · 2006 to 2026
$5.2M
2/2-D-Cycloserine Augmentation of CBT for Pediatric OCDR01MH093402 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI GELLER, DANIEL A · 2011 to 2014
$1.7M
1/2-D-Cycloserine Augmentation of CBT for Pediatric OCDR01MH093381 · NIMH · UNIVERSITY OF SOUTH FLORIDA · PI STORCH, ERIC A. · 2011 to 2014
$1.2M
Targeting Attentional and Cognitive Control to Enhance the Transdiagnostic Treatment of Repetitive Negative ThinkingK23MH120351 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI JACOBY, RYAN J · 2020 to 2024
$977k
NIMH NIH HHS K23 MH120351NIMH NIH HHS R01 MH093381NIMH NIH HHS R01 MH093402NIMH NIH HHS T32 MH073517
6 · The paper itself

Abstract

Family accommodation (FA) is key in the maintenance of OCD. However, most studies are cross-sectional, and have not identified long-term trajectories and correlates of FA changes over treatment. This study investigated changes in clinician-rated FA over 10 sessions of cognitive behavioral therapy (CBT) for 142 children with OCD, as well as several key predictors/correlates: (a) clinician-rated OCD symptom severity, (b) child- and parent-rated functional impairment, (c) parent-rated treatment expectancies, and (d) child- and parent-rated therapeutic alliance. Multi-level models indicated that FA changed significantly during treatment, with gains maintained over 6-months. Baseline clinician-rated OCD severity did not predict changes in FA. Significant interactions indicated that children with higher child- and parent-rated impairment exhibited greater FA improvements over treatment (versus children with lower impairment). Child- and parent-rated therapeutic alliance and parent-rated expectancies did not predict FA changes. Finally, FA mediated the relationship between OCD severity and parent- (but not child-) rated impairment. Reverse mediation models were also significant. Findings indicate that CBT can successfully reduce FA (a) even if children experience high OCD severity and interference in school, relationships, and family life, and (b) regardless of non-specific factors like treatment expectancies and alliance. FA reductions are an important mechanism mediating treatment response.

Indexed as

Cognitive Behavioral TherapyImplosive TherapyObsessive-Compulsive DisorderChildCross-Sectional StudiesHumansTreatment OutcomeAccommodationCognitive Behavioral Therapy (CBT)FamilyObsessive Compulsive Disorder (OCD)Pediatric

Identifiers

PMID34428688
PMCPMC8925412
OpenAlexW3190473803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.