Evidence map›Paper›PMID 34428670›Full record

ArticleJournal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology2021

Intramuscular pressure of human tibialis anterior muscle detects age-related changes in muscle performance.

Filiz Ateş, Krista Coleman-Wood, William Litchy, Kenton R Kaufman

Abstract read
In one paragraph

Article in Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Filiz AteşAerospace Engineering and Geodesy, University of Stuttgart, Stuttgart, Germany; Motion Analysis Laboratory, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Krista Coleman-WoodMotion Analysis Laboratory, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
William LitchyDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Kenton R KaufmanMotion Analysis Laboratory, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address: Kaufman.Kenton@mayo.edu.

Funding

MICROSENSOR FOR INTRAMUSCULAR PRESSURE MEASUREMENTR01HD031476 · NICHD · MAYO CLINIC ROCHESTER · PI KAUFMAN, KENTON R. · 1994 to 2014
$5.3M
NICHD NIH HHS R01 HD031476
6 · The paper itself

Abstract

Intramuscular pressure (IMP) reflects forces produced by a muscle. Age is one of the determinants of skeletal muscle performance. The present study aimed to test whether IMP mirrors known age-related muscular changes. We simultaneously measured the tibialis anterior (TA) IMP, compound muscle action potential (CMAP), and ankle torque in thirteen older adults (60-80 years old) in vivo by applying different stimulation intensities and frequencies. We found significant positive correlations between the stimulation intensity and IMP and CMAP. Increasing stimulation frequency caused ankle torque and IMP to increase. The electromechanical delay (EMD) (36 ms) was longer than the onset of IMP (IMPD) (29 ms). Compared to the previously published data collected from young adults (21-40 years old) in identical conditions, the TA CMAP and IMP of older adults at maximum intensity of stimulation were 23.8% and 39.6% lower, respectively. For different stimulation frequencies, CMAP, IMP, as well as ankle torque of older adults were 20.5%, 24.2%, and 13.2% lower, respectively. Surprisingly, the EMD did not exhibit any difference between young and older adults and the IMPD was consistent with the EMD. Data supporting the hypotheses suggest that IMP measurement is an indicator of muscle performance in older adults.

Indexed as

AnkleMuscle, SkeletalAdultAgedAged, 80 and overAnkle JointElectromyographyHumansMiddle AgedTorqueYoung AdultAgingAnkle torqueCompound Muscle Action Potential (CMAP)Electromechanical delay (EMD)Intramuscular pressure (IMP)Sarcopenia

Identifiers

PMID34428670
PMCPMC8455447

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.