Evidence map›Paper›PMID 34428642›Full record

Trial reportBehaviour research and therapy2021

Outcomes of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) in a community setting: Unpacking comorbidity.

Laurel D Sarfan, Heather E Hilmoe, Nicole B Gumport, Caitlin E Gasperetti, Garret G Zieve, Allison G Harvey

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behaviour research and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
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  8. Review
  9. Article
  10. The sleep-circadian interface: A window into mental disorders.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laurel D SarfanUniversity of California, Berkeley, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: sarfanld@berkeley.edu.
Heather E HilmoeUniversity of California, Berkeley, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: heatherhilmoe@berkeley.edu.
Nicole B GumportUniversity of California, Berkeley, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: ngumport@berkeley.edu.
Caitlin E GasperettiUniversity of California, Berkeley, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: cegg@berkeley.edu.
Garret G ZieveUniversity of California, Berkeley, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: ggzieve@berkeley.edu.
Allison G HarveyUniversity of California, Berkeley, 2121 Berkeley Way, Berkeley, CA, 94720, USA. Electronic address: aharvey@berkeley.edu.

Funding

Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health.R01MH120147 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARVEY, ALLISON G · 2019 to 2023
$3.9M
A transdiagnostic sleep and circadian treatment to improve community SMI outcomesR01MH105513 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARVEY, ALLISON G · 2015 to 2018
$2.8M
NIMH NIH HHS R01 MH105513NIMH NIH HHS R01 MH120147
6 · The paper itself

Abstract

objectiveComorbidity and subdiagnostic symptoms are understudied for sleep and circadian problems. We evaluated 1) impairment associated with (a) number of sleep and circadian problems and (b) diagnostic threshold (full diagnosis vs. subdiagnostic symptoms), and 2) Transdiagnostic Sleep and Circadian Intervention (TranS-C) outcomes for participants with specific sleep and circadian problems.

methodCommunity participants (N = 121) with serious mental illness and sleep and circadian problem(s) were randomized to receive TranS-C plus usual care (TranS-C + UC) or usual care plus delayed TranS-C (UC-DT). Overall impairment, psychiatric symptoms, and sleep and circadian dysfunction were assessed at pre-treatment, post-treatment, and 6-month follow-up.

resultsHigher numbers of sleep and circadian problems, versus one problem, were associated with worse overall impairment, psychiatric symptoms, and sleep and circadian dysfunction (ps < 0.05, ω

conclusionHigher numbers of sleep and circadian problems, not diagnostic threshold, were associated with greater impairment. Transdiagnostic utility of TranS-C + UC was supported.

Indexed as

SleepSleep Initiation and Maintenance DisordersCircadian RhythmComorbidityHumansCircadianCommunity mental healthComorbidSerious mental illnessSleepTransdiagnostic

Identifiers

PMID34428642
PMCPMC10927273

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.