ReviewArchivos de cardiologia de Mexico2022
Mechanisms of platypnea-orthodeoxia syndrome.
Review in Archivos de cardiologia de Mexico, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Heart-Rate-Dependent Right-to-Left Shunting Through a Patent Foramen Ovale in Severe Right Ventricular Dysfunction: A Case Report.Journal of clinical medicine · 2026Article
- Platypnea-Orthodeoxia Syndrome: A Distinct Entity or a Phenotype of Dynamic Shunting?JACC. Case reports · 2026Article
- Insight Into the Multifactorial Nature of Platypnea-Orthodeoxia Syndrome: Not Just a Solo.JACC. Case reports · 2026Article
- Platypnea-orthodeoxia syndrome treated by percutaneous patent foramen ovale closure: a case report and review of the literature.Journal of medical case reports · 2026Review
- Anesthetic management of Platypnea-orthodeoxia syndrome in a young patient with residual atrial septal defect following congenital heart surgery.JA clinical reports · 2025Article
- Platypnea-Orthodeoxia Syndrome Revealing an Undiagnosed Patent Foramen Ovale: A Case Report.Cureus · 2025Article
- An unusual cause of refractory hypoxaemia after hiatus hernia surgery: a case report of platypnoea-orthodeoxia syndrome.Perioperative medicine (London, England) · 2025Article
- Article
- Platypnea-Orthodeoxia Syndrome Post-Pneumonectomy: A Case of Right-To-Left Shunting and Successful PFO Closure.Clinical case reports · 2025Article
- Platypnea-Orthodeoxia Syndrome From Atrial Septal Defects: A Rare Primum Case and Literature Review.Cureus · 2025Article
- Turning the Tide: Unraveling Aortic Dynamics and Patent Foramen Ovale in Platypnea-Orthodeoxia Syndrome.JACC. Case reports · 2025Article
- Platypnea-Orthodeoxia Syndrome Secondary to Patent Foramen Ovale and Pulmonary Thromboembolism.Cureus · 2025Article
- Management of coexisting patent foramen ovale and pulmonary arteriovenous malformation: a case report of sequential closure.European heart journal. Case reports · 2025Article
- Article
- A patient with unexplained hypoxemia after a fall diagnosed with platypnea orthodeoxia syndrome: approaches to resolving discrepancies between level of hypoxemia and clinical presentation.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
- When hypoxemia does not respond to oxygen therapy: a case of platypnea-orthodeoxia syndrome.Archivos de cardiologia de Mexico · 2024Article
- Article
- A Rare Case of Platypnea-Orthodeoxia Syndrome in a Patient With Undiagnosed Atrial Septal Defect.Cureus · 2024Article
- Platypnea-Orthodeoxia Syndrome: Two Case Reports.Cureus · 2023Article
- Platypnoea-orthodeoxia syndrome affects nocturnal oxygen desaturation: A case report.Respirology case reports · 2023Article
Corrections and comments
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1 author.
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Abstract
Platypnea orthodeoxia syndrome (POS) is a clinical entity described in the middle of the last century. It is characterized by dyspnea and hypoxemia triggered by standing and relieved with recumbency. The diagnosis is predominately clinical. The degree of hypoxemia is variable; however, the diagnostic criteria include the decrease in arterial oxygen pressure more than 4 mmHg or oxygen saturation more than 5%. Even though many diseases cause this syndrome, there are only two responsible mechanisms, intracardiac, and intrapulmonary shunts. The coexistence of diverse structural and physiological abnormalities joined to gravitational forces that induce blood shunt after standing is crucial in each mechanism. The intracardiac mechanism is characterized by right to left blood shunt through atrial septal communications and, the right atrium pressure could be normal or increased. In addition, some patients have one or more coexistent aortic, spinal, or intracardiac alterations. The intrapulmonary mechanism is less frequent and is caused by parenchymal or vascular pathologies. Transthoracic echocardiogram is the first diagnostic modality; however, understanding the pathophysiology is the key for a rational diagnostic approach and subsequent diagnostic studies. Treatment is possible and effective in the majority of intracardiac mechanisms and some intrapulmonary. This review focuses on the pathophysiologic mechanisms of POS and their diagnostic workup.
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