Evidence map›Paper›PMID 34428130›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Association between Intermittent Hypoxemia and Severe Bronchopulmonary Dysplasia in Preterm Infants.

Erik A Jensen, Robin K Whyte, Barbara Schmidt, Dirk Bassler, Nestor E Vain, Robin S Roberts, Canadian Oxygen Trial Investigators

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Time spent within the SpOBMJ open respiratory research · 2026
    Trial
  4. Trial
  5. Trial
  6. Article
  7. Titrating cumulative neonatal hyperoxia in mice to model bronchopulmonary dysplasia severities.American journal of respiratory cell and molecular biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Defining apnea of prematurity is messy.Pediatric research · 2026
    Article
  14. Article
  15. Review
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Erik A JensenDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania.
Robin K WhyteDepartment of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.
Barbara SchmidtDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pennsylvania.
Dirk BasslerDepartment of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Nestor E VainSchool of Medicine, University of Buenos Aires, Buenos Aires, Argentina; and.
Robin S RobertsDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Canadian Oxygen Trial Investigators
Children's Hospital of Philadelphia · USDalhousie University · CAImpact · CAUniversidad de Buenos Aires · ARUniversity of Zurich · CH

Funding

Microbiome of the Airway and the Risk for Bronchopulmonary Dysplasia in the Lungs of Extreme Preterms: The MARBLE StudyK23HL136843 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI JENSEN, ERIK ALLEN · 2018 to 2022
$819k
Phase 1 trial of inhaled tobramycin in very preterm infants with bronchopulmonary dysplasiaR34HL155690 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI DOWNES, KEVIN JAMES, JENSEN, ERIK ALLEN · 2021 to 2023
$792k
NHLBI NIH HHS K23 HL136843NHLBI NIH HHS R34 HL155690
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bronchopulmonary DysplasiaCanadaFemaleHumansHypoxiaInfant, Extremely PrematureInfant, NewbornMaleRespiratory Distress Syndrome, Newbornbronchopulmonary dysplasiaextremely preterm infantintermittent hypoxemiapulse oximetry

Identifiers

PMID34428130
PMCPMC8759313
OpenAlexW3195726817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.