Evidence map›Paper›PMID 34427972›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2021

Quantifying displacement of urogenital organs after abdominoperineal resection for rectal cancer.

Sarah Sharabiany, Gaby J Strijk, Robin D Blok, Colin G Ferrett, Jaap Stoker, Christopher Cunningham, Jarmila D W van der Bilt, Anna A W van Geloven, Wilhelmus A Bemelman, Roel Hompes and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Quantifying displacement of urogenital organs after abdominoperineal resection for rectal cancer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Sarah SharabianyDepartment of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0003-2222-2037
Gaby J StrijkDepartment of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
Robin D BlokDepartment of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
Colin G FerrettDepartment of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Jaap StokerDepartment of Radiology, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
Christopher CunninghamDepartment of Colorectal Surgery, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Jarmila D W van der BiltDepartment of Surgery, Flevo Hospital, Almere, The Netherlands.
Anna A W van GelovenDepartment of Surgery, Tergooi Hospital, Hilversum, The Netherlands.
Wilhelmus A BemelmanDepartment of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
Roel HompesDepartment of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
Gijsbert D MustersDepartment of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.
Pieter J TanisDepartment of Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-3146-3310
Amsterdam University Medical Centers · NLChurchill Hospital · GBFlevoziekenhuis · NLOxford University Hospitals NHS Trust · GBTergooi · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aimed to quantify displacement of urogenital organs after abdominoperineal resection (APR), and to explore patient and treatment characteristics associated with displacement.

methodPatients from 16 centres who underwent APR for primary or recurrent rectal cancer (2001-2018) with evaluable preoperative and 6-18 months postoperative radiological imaging were included in the study. Anatomical landmarks on sagittal images were related to a coordinate system based on reference lines between fixed bony structures and absolute displacements were calculated using the Pythagorean theorem. Rotation of landmarks was measured relative to a pubic-S5 reference line.

resultsThere were 248 patients included of which 171 were men and 77 women. The median displacement of the internal urethral orifice was 25 mm in men (maximum 65), and 17 mm in women (maximum 50). Rotation of the internal urethral orifice was in a caudal direction in 160/170 (94%) of men and 65/73 (89%) of women, with a median of 32 degrees (maximum 85) and 33 degrees (maximum 83), respectively. Displacements of the posterior bladder wall, distal end of prostatic urethra and cervix were significantly correlated with the internal urethral orifice. In linear regression analysis, biological mesh reconstruction of the pelvic floor and visceral interposition were significantly associated with increased displacement of the internal urethral orifice, and female gender and any filling of the presacral space with decreased displacement.

conclusionsSubstantial absolute displacement and rotation of urogenital organs after APR for rectal cancer were observed, but with high variability among both men and women, and being significantly associated with reconstructive interventions.

Indexed as

ProctectomyRectal NeoplasmsFemaleHumansMaleNeoplasm Recurrence, LocalPelvic FloorPerineumUrethraabdominoperineal resectionquantification of displacementrectal cancerurogenital organs

Identifiers

PMID34427972
PMCPMC9291959
OpenAlexW3194740862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.