Evidence map›Paper›PMID 34427760›Full record

ArticleRheumatology international2021

Managing ANCA-associated vasculitis during the COVID-19 pandemic: results from an online survey.

Chirag Rajkumar Kopp, Gsrsnk Naidu, Durga Prasanna Misra, Prateek Deo, Roopesh Sai Jakulla, Kavita Makan, Ajesh Maharaj, Vikas Agarwal, Aman Sharma

Open access · bronzeAbstract read
In one paragraph

Article in Rheumatology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Chirag Rajkumar KoppClinical Immunology and Rheumatology Division, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.ORCID http://orcid.org/0000-0002-2304-1361
Gsrsnk NaiduClinical Immunology and Rheumatology Division, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Durga Prasanna MisraDepartment of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Uttar Pradesh, Lucknow, India.ORCID http://orcid.org/0000-0002-5035-7396
Prateek DeoClinical Immunology and Rheumatology Division, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Roopesh Sai JakullaDepartment of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Kavita MakanDivision of Rheumatology, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Ajesh MaharajLife Healthcare, Westville, Durban, South Africa.
Vikas AgarwalDepartment of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Uttar Pradesh, Lucknow, India.ORCID http://orcid.org/0000-0002-4508-1233
Aman SharmaClinical Immunology and Rheumatology Division, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India. amansharma74@yahoo.com.ORCID http://orcid.org/0000-0003-0813-1243
Post Graduate Institute of Medical Education and Research · INSanjay Gandhi Post Graduate Institute of Medical Sciences · INBroadReach Healthcare (South Africa) · ZAUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of ANCA-associated vasculitis (AAV) during the COVID-19 pandemic poses unique therapeutic challenges. An online survey was conducted to understand physician's choices for treating AAV during the COVID-19 pandemic. Web-based survey featuring nineteen questions was circulated amongst physicians across various specialties. The responses regarding immunosuppressive therapy for remission induction and maintenance, COVID-19 testing, and preventive measures were recorded. A total of 304 responses were recorded. Most of the respondents were from India (83.9%) and comprised rheumatologists (66%) in practice for ≥ 5 years (71%). Though a majority preferred Rituximab or intravenous cyclophosphamide (CYC) as a remission induction agent, a significant proportion opted for oral CYC and mycophenolate mofetil (MMF) also. Only one-third wanted to test for COVID-19 before initiating immunosuppressive therapy in patients with organ/life-threatening manifestations. Rituximab was the most favored maintenance therapy (47%), followed by azathioprine, MMF, and methotrexate. The results of this focused survey of managing AAV patients depict the real-world dilemmas and physicians' choices in this setting.

Indexed as

Practice Patterns, Physicians'AdultAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisCOVID-19COVID-19 TestingFemaleHumansImmunosuppression TherapyImmunosuppressive AgentsMaleMiddle AgedPandemicsRemission InductionRheumatologySARS-CoV-2Surveys and QuestionnairesImmunosuppressive AgentsAgentsANCA-associated vasculitisCOVID-19ImmunosuppressiveOnline survey

Identifiers

PMID34427760
PMCPMC8382578
OpenAlexW3195652209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.