Evidence map›Paper›PMID 34427514›Full record

ArticlemSystems2021

Proteome Dynamics during Antibiotic Persistence and Resuscitation.

Maja Semanjski, Fabio Lino Gratani, Till Englert, Payal Nashier, Viktor Beke, Nicolas Nalpas, Elsa Germain, Shilpa George, Christiane Wolz, Kenn Gerdes and 1 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Proteostasis-targeted antibacterial strategies.Journal of microbiology (Seoul, Korea) · 2026
    Review
  5. Review
  6. Molecular Basis of Persister Awakening and Lag-Phase Recovery inInternational journal of molecular sciences · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Maja Semanjski *Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Fabio Lino Gratani *Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Till EnglertQuantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Payal NashierQuantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Viktor BekeQuantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Nicolas NalpasQuantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Elsa GermainCentre for Bacterial Stress Response and Persistence, Section for Functional Genomics, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Shilpa GeorgeMedical Microbiology and Hygiene, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Christiane WolzMedical Microbiology and Hygiene, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
Kenn GerdesCentre for Bacterial Stress Response and Persistence, Section for Functional Genomics, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Boris MacekQuantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany.
University of Tübingen · DECentre National de la Recherche Scientifique · FRUniversity of Copenhagen · DK

Funding

Danmarks Grundforskningsfond (DNRF) DNRF120Deutsche Forschungsgemeinschaft (DFG) EXC 2124EC | H2020 | H2020 Priority Excellent Science | H2020 Marie Skłodowska-Curie Actions (MSCA) 955626German-Israeli Foundation for Scientific Research and Development (GIF) I-1464-416.13/2018Novo Nordisk Fonden (NNF)
6 · The paper itself

Abstract

During antibiotic persistence, bacterial cells become transiently tolerant to antibiotics by restraining their growth and metabolic activity. Detailed molecular characterization of antibiotic persistence is hindered by low count of persisting cells and the need for their isolation. Here, we used sustained addition of stable isotope-labeled lysine to selectively label the proteome during

Indexed as

bacteriapersistenceproteomicsresuscitationSILAC

Identifiers

PMID34427514
PMCPMC8407246
OpenAlexW3193993691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.