Evidence map›Paper›PMID 34427510›Full record

ArticlemSystems2021

How the Physical Environment Shapes the Microbiota.

Carolina Tropini

Abstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Diagnosing and engineering gut microbiomes.EMBO molecular medicine · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. The gut microbiota and its biogeography.Nature reviews. Microbiology · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Carolina TropiniSchool of Biomedical Engineering, University of British Columbia, Vancouver, Canada.

Funding

Canada Foundation for Innovation (CFI) 38277Canadian Institute for Advanced Research (ICRA) GS20-011Crohn's and Colitis Canada (Crohn et Colite Canada) 625155Gouvernement du Canada | Canadian Institutes of Health Research (CIHR) FASF19-04421Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2019-04591Johnson & Johnson Women in STEM2D 15007Michael Smith Foundation for Health Research (MSFHR) 18239Paul G. Allen Frontiers Group 200716Scialog Research Corporation for Science Advancement, Frederick Gardner Cottrell Foundation, Paul G. Allen Frontiers Group 27872W. Garfield Weston Foundation AWD-016701
6 · The paper itself

Abstract

Living systems, from micro- to macro-scales, are strongly impacted by physical factors such as temperature, pH, and the concentration of compounds in their surrounding environment. In the macro-world, it is obvious that small changes in these parameters can have profound, and even devastating, impacts on an ecosystem. For example, in the case of global warming, a change in climate, and specifically a few degrees in temperature, has taken one million species of animals to the brink of extinction. Scale things down 6 orders of magnitude, our gut microbiota also experiences similar changes in temperature due to disease. In this highly competitive environment, physical perturbations inflict long-term consequences on the microbiota ecosystem and, in turn, on the host organism. My laboratory is exploring the feedback between the gut's physical environment, the microbiota, and disease. Our research highlights the importance of measuring physical parameters for the prediction of microbial dynamics and microbiota therapies.

Indexed as

gut biogeographymicrobiotaphysical perturbations

Identifiers

PMID34427510
PMCPMC8407308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.