Evidence map›Paper›PMID 34427236›Full record

Observational studyIndian journal of ophthalmology2021

A cross-sectional study to determine the normal corneal epithelial thickness in Indian population using 9-mm wide optical coherence tomography scans.

Abhishek A Hoshing, Seema Bhosale, Monica P Samant, Aditya Bamne, Huma Kalyankar

Open access · diamondAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abhishek A HoshingDepartment of Cornea and Refractive Surgery, Strabismus and Neuro-Ophthalmology, Laxmi Eye Institute, Panvel; Department of Ophthalmology, Apollo Hospitals, Navi Mumbai, Maharashtra, India.
Seema BhosaleDepartment of Cataract Services, Strabismus and Neuro-Ophthalmology, Laxmi Eye Institute, Panvel, Maharashtra, India.
Monica P SamantDepartment of Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology, Laxmi Eye Institute, Panvel, Maharashtra, India.
Aditya BamneDepartment of Clinical Optometry, Laxmi Eye Institute, Panvel, Maharashtra, India.
Huma KalyankarDepartment of Clinical Optometry, Laxmi Eye Institute, Panvel, Maharashtra, India.
Apollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the corneal epithelial thickness with 9-mm scans of optical coherence tomography in normal Indians with appropriate representation of all age groups.

methodsThis was a cross-sectional observational study. 263 patients were divided into the age groups 5-20 years, 21-35 years, 36-50 years and more than 51 years were recruited for the study. All patients underwent a detailed ophthalmic examination. Patients found to have any ocular surface or intraocular disease condition (except cataract and refractive error), or who had undergone any ophthalmic surgery in the past, or had corneal topography changes suggestive of corneal ectasias (screened in patients with astigmatism more than 3 diopters) or had been continuously using any topical medication in either eye for a period of 3 months or more with the last instillation being within 1 month of inclusion in the study were excluded. All subjects underwent corneal epithelial thickness measurement with anterior segment optical coherence tomography (AS-OCT) on the Avanti OCT (Model RTVueXR1002, Optovue, USA). The corneal epithelial thickness (CET) data from 25 sectors in each eye were analyzed.

results263 right and left eyes of 263 patients were analyzed in the study. Mean CETs in the central 2 mm zone were 54.13 ± 4.51 μm and 54.37 ± 3.75 μm for the right and left eyes, respectively. The superior peripheral sectors and inferior paracentral sectors were the thinnest and the thickest sectors, respectively, in both eyes.

conclusionCET parameters for Indian eyes are comparable to those reported from racially distinct and geographically distant study subjects.

Indexed as

Epithelium, CornealTomography, Optical CoherenceAdolescentAdultChildChild, PreschoolCorneaCorneal PachymetryCross-Sectional StudiesHumansYoung Adultcorneal epitheliumEpithelium thicknessIndiannormative dataoptical coherence tomogrpahy

Identifiers

PMID34427236
PMCPMC8544085
OpenAlexW3193618645

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.