Evidence map›Paper›PMID 34427056›Full record

ArticleInfluenza and other respiratory viruses2022

Change in patterns of hospitalization for influenza during COVID-19 surges.

Sindhaghatta Venkatram, Anuhya Alapati, Arundhati Dileep, Gilda Diaz-Fuentes

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sindhaghatta VenkatramDivision of Pulmonary and Critical Care Medicine, BronxCare Health System, Affiliated with Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-2206-9597
Anuhya AlapatiDivision of Pulmonary and Critical Care Medicine, BronxCare Health System, Affiliated with Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Arundhati DileepDivision of Pulmonary and Critical Care Medicine, BronxCare Health System, Affiliated with Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gilda Diaz-FuentesDivision of Pulmonary and Critical Care Medicine, BronxCare Health System, Affiliated with Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mount Sinai Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHospitalization due to influenza has been stable in recent years. In March 2020, New York was an epicenter for coronavirus disease 2019 (COVID-19). Because influenza and COVID-19 present similarly, there were serious concerns that coinfection of these viruses would burden the healthcare system. We compared incidence and outcomes of patients hospitalized with influenza before and during COVID-19 (seasons 2017-2021).

methodsWe conducted a retrospective study evaluating hospitalized patients with influenza. Four influenza seasons were evaluated, 2017-2021, pre- and during COVID-19 pandemic. We compared incidence of influenza and clinical outcomes across the seasons.

resultsWe found 412 patients hospitalized due to influenza in the study period; 394 had influenza, and 18 had both influenza and COVID-19 infections. Demographics across the four influenza seasons were comparable; the cohort was predominantly female (61%) and had an average age of 60 years old. Comorbid conditions were common. No outcome differences were found for patients with influenza when comparing influenza seasons prior to and during the COVID-19 pandemic. The mortality for the entire cohort was 6.5%. During the COVID-19 pandemic, there were 18 (4.4%) influenza patients coinfected with COVID-19 and 32 (7.8%) patients with bacterial super infection. Predictors of mortality in patients with influenza included presence of shock, heart failure, bacterial pneumonia, and use of mechanical ventilation. Coinfection with COVID-19 did not increase mortality.

conclusionWe observed a significant decrease in the incidence of hospitalization due to influenza during the COVID-19 pandemic. Clinical presentations and outcomes for patients with influenza remain stable. Being aware of possible increased mortality for patients with both influenza and bacterial pneumonia is important. Although coinfection with COVID-19 did not increase mortality in influenza patients, identifying the specific virus responsible for infections has major therapeutic implications.

Indexed as

CoinfectionCOVID-19Influenza, HumanFemaleHospitalizationHumansMiddle AgedPandemicsRetrospective StudiesSARS-CoV-2COVID-19influenzamechanical ventilationmortalitypneumonia

Identifiers

PMID34427056
PMCPMC8653106
OpenAlexW3193434989

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.