ArticleEnvironmental science and pollution research international2022
Effect of induced sublethal intoxication with neonicotinoid insecticides on Egyptian toads (Sclerophrys regularis).
Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- The impact of chemical pollution across major life transitions: a meta-analysis on oxidative stress in amphibians.Proceedings. Biological sciences · 2024Pooled it
- Sublethal Clothianidin Exposure Impairs Development, Thyroid Hormones, Locomotion and Predation inToxics · 2026Article
- Impact of acetamiprid on fatty acid composition of the central nervous system in honey bees.Scientific reports · 2025Article
- Selected neonicotinoids and associated risk for aquatic organisms.Veterinarni medicina · 2023Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
The toxicity role of insecticides affecting nontarget vertebrate of wildlife population has become essential subject to focus on. In this vein, the current study aimed to illustrate some biochemical and histopathological alterations induced by two neonicotinoids in Egyptian toads. Forty-five toads were collected and divided equally into three groups (15 toads/group): control group, thiamethoxam group, and acetamiprid group. Both treatment groups received thiamethoxam and acetamiprid (30 and 40 mg/L, respectively) four times within 12 days for induction of sublethal toxicity. Blood and liver tissue samples were collected. Both insecticides cause the same changes, but acetamiprid group exhibited a pronounced significant (P ≥ 0.001) effect than thiamethoxam group on increasing serum lipid profile, ALT, and AST. Moreover, acetamiprid showed a significant (P ≥ 0.001) decrease in hepatic total protein, GSH, and SOD and increase in MDA levels in comparison with thiamethoxam and control groups, respectively. The histopathological hepatic examination showed markable alterations in hepatic architecture in treatment groups that was distinct in acetamiprid group. Finally, our findings illustrate the indirect effect of neonicotinoids on toads and may realize their life-threatening factors. Graphical Abstract.
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