Evidence map›Paper›PMID 34426772›Full record

ArticleCase reports in cardiology2021

The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients.

Ju Young Bae, Khalil Ian Hussein, Christopher John Howes, John Francis Setaro

Abstract readCase Reports
In one paragraph

Article in Case reports in cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ju Young BaeDepartment of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USA.ORCID https://orcid.org/0000-0001-8509-7099
Khalil Ian HusseinDepartment of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USA.ORCID https://orcid.org/0000-0001-9095-0103
Christopher John HowesDepartment of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USA.ORCID https://orcid.org/0000-0003-2718-5693
John Francis SetaroDepartment of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USA.ORCID https://orcid.org/0000-0001-5367-9529

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

By July 2021, the United States had over 34.4 million confirmed COVID-19 cases. Various cardiovascular manifestations of COVID-19 have been reported including ST-elevation myocardial infarction (STEMI), and there is concern that SARS-CoV-2 may be associated with a higher thrombus burden. We performed a retrospective chart review of 535 adult patients with COVID-19 admitted at Yale-New Haven Health Greenwich Hospital from February 1, 2020, to May 13, 2020. All admitted patients had undergone testing for serum troponin I and various inflammatory markers, and we identified three patients who were diagnosed with acute STEMI. Data was collected via manual chart review and included patient demographics, comorbidities, laboratory tests, electrocardiogram (ECG) results, echocardiography results, diagnoses during hospitalization, inpatient therapies, and outcomes including length of hospital stay, revascularization results, and mortality. Three of our patients had obstructive coronary artery disease confirmed via angiography. One subject was noted to display vasospasm in addition to coronary atherosclerotic obstruction and refractory thrombus formation. Among our patients with COVID-19 and STEMI, presentations were variable in terms of timing of onset of ECG changes, age, gender, race, comorbidities, symptomology, and outcomes.

Identifiers

PMID34426772
PMCPMC8379640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.