Evidence map›Paper›PMID 34426738›Full record

Trial reportNeural plasticity2021

Contralesional Cathodal Transcranial Direct Current Stimulation Does Not Enhance Upper Limb Function in Subacute Stroke: A Pilot Randomized Clinical Trial.

Danielle De S Boasquevisque, Larissa Servinsckins, Joselisa P Q de Paiva, Daniel G Dos Santos, Priscila Soares, Danielle S Pires, Jed A Meltzer, Ela B Plow, Paloma F de Freitas, Danielli S Speciali and 5 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Neural plasticity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Comparative efficacy of different noninvasive brain stimulation protocols on upper-extremity motor function and activities of daily living after stroke: a systematic review and network meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Danielle De S BoasquevisqueHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.ORCID 0000-0003-0402-4686
Larissa ServinsckinsHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Joselisa P Q de PaivaHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.ORCID 0000-0001-7487-397X
Daniel G Dos SantosHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Priscila SoaresHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Danielle S PiresHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Jed A MeltzerRotman Research Institute, Baycrest Centre, Toronto, Canada M6A2E.ORCID 0000-0002-4301-1901
Ela B PlowCleveland Clinic Foundation, Cleveland 44195, USA.
Paloma F de FreitasHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Danielli S SpecialiHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Priscila LopesHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Mario F P PeresHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.ORCID 0000-0002-0068-1905
Gisele S SilvaHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.ORCID 0000-0002-3247-3123
Shirley LacerdaHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.
Adriana B ConfortoHospital Israelita Albert Einstein, São Paulo 05652-900, Brazil.ORCID 0000-0001-7869-3490
Hospital Israelita Albert Einstein · BRBaycrest Hospital · CACleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial direct current stimulation (tDCS) has the potential to improve upper limb motor outcomes after stroke. According to the assumption of interhemispheric inhibition, excessive inhibition from the motor cortex of the unaffected hemisphere to the motor cortex of the affected hemisphere may worsen upper limb motor recovery after stroke. We evaluated the effects of active cathodal tDCS of the primary motor cortex of the unaffected hemisphere (ctDCSM1

Indexed as

Transcranial Direct Current StimulationAgedAged, 80 and overDouble-Blind MethodFemaleHumansMaleMiddle AgedMotor CortexPilot ProjectsRecovery of FunctionStrokeStroke RehabilitationTreatment OutcomeUpper Extremity

Identifiers

PMID34426738
PMCPMC8380180
OpenAlexW3191885134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.