ArticleNature immunology2021
Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity.
Abstract read
In one paragraph
Article in Nature immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 1 pooled it
15.3field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
136 citing papers in PubMed, 1 synthesis or guideline pooled it, 218 citations in OpenAlex.
- The soldiers needed to be awakened: Tumor-infiltrating immune cells.Frontiers in genetics · 2022Pooled it
- H3.3 chaperone Hira primes the effector program and function of regulatory T cells.Science advances · 2026Article
- Pregnancy-induced tissue-resident memory-like T cells contribute to tumor control in breast cancer.Nature immunology · 2026Article
- Mechanosensing by T cells promotes a tissue-resident memory transcriptional program.Nature immunology · 2026Article
- A pathogenic CD8⁺ TNature communications · 2026Article
- Ovarian localization drives IL-7R-dependent CD8 coreceptor expression in peripheral double-negative T cells.Cellular and molecular life sciences : CMLS · 2026Article
- Temporal Dissection of TGF-β signaling reveals differential impact during female reproductive mucosal CD8 resident memory T cell differentiation.Mucosal immunology · 2026Article
- Article
- Coincident epithelial signals restrain commensal-specific CD8αβbioRxiv : the preprint server for biology · 2026Article
- Living rent free in your head: resident memory T cells.ImmunoHorizons · 2026Review
- Peripheral vaccination-induced brain-resident memory CD8+ T cells durably protect mice against intracranial malignancy.The Journal of clinical investigation · 2026Article
- KLF2 overrides the resident memory CD8 T cell differentiation program, in opposition to KLF3.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Enumeration, Phenotyping, and Clinical Associations of Tissue-Resident T Cells in the Ecto- and Endocervix of Women Attending a Colposcopy Clinic.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Article
- IL-6 is one of the key factors in the formation of gut tissue resident memory T cells from Naïve T cells.PLoS pathogens · 2026Article
- Distinct commensal bacteria in human nasopharyngeal lymphoid tissue associated with localized immunological memory.iScience · 2026Article
- In Vitro Resident Memory CD8 T Cell Differentiation Using Epithelial Organoid-T Cell Co-culture System.Journal of visualized experiments : JoVE · 2026Article
- Cancer Stem Cells Shift Metabolite Acetyl-Coenzyme A to Abrogate the Differentiation of CD103Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- BHLHE40 Orchestrates Effector Tissue-Resident Memory CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- CXCR6 promotes dermal CD8+ T cell survival and transition to long-term tissue residence.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- The orphan nuclear receptor NR4A3 is dispensable for resident memory CD8+ T-cell generation.ImmunoHorizons · 2026Article
76 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
26 authors at 7 institutions in 3 countries.
Susan N ChristoDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Maximilien EvrardDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-2105-1160
Simone L ParkDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Luke C GandolfoDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Thomas N BurnDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Raissa FonsecaDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Dane M NewmanDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Yannick O AlexandreDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Nicholas CollinsDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Natasha M ZamudioDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Fernando Souza-Fonseca-GuimaraesTranslational Research Institute, Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
Daniel G PellicciDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
David ChisangaWalter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-0421-3957
Wei ShiWalter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.
Laurent BartholinCentre de Recherche en Cancérologie de Lyon (CRCL), Université de Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Lyon, France.
Gabrielle T BelzWalter and Eliza Hall Institute for Medical Research, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-9660-9587
Nicholas D HuntingtonDepartment of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-5267-7211
Andrew LucasMedical School, University of Western Australia, Perth, Western Australia, Australia.
Michaela LucasMedical School, University of Western Australia, Perth, Western Australia, Australia.
Scott N MuellerDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
William R HeathDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0001-9670-259X
Florent GinhouxSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.ORCID http://orcid.org/0000-0002-2857-7755
Terence P SpeedSchool of Mathematics and Statistics, The University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-5403-7998
Francis R CarboneDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Axel KalliesDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-6312-6968
Laura K MackayDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia. lkmackay@unimelb.edu.au.ORCID http://orcid.org/0000-0002-8496-6632
The University of Melbourne · AUThe University of Western Australia · AUTranslational Research Institute · AUWalter and Eliza Hall Institute of Medical Research · AUAgency for Science, Technology and Research · SGMonash University · AUUniversité Claude Bernard Lyon 1 · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tissue-resident memory T (T
Indexed as
AnimalsAntigens, CDCD8-Positive T-LymphocytesCell DifferentiationCell PlasticityCellular MicroenvironmentFemaleImmunologic MemoryIntegrin alpha ChainsMiceMice, Inbred C57BLMice, KnockoutSignal TransductionTransforming Growth Factor beta1alpha E integrinsAntigens, CDIntegrin alpha ChainsTgfb1 protein, mouseTransforming Growth Factor beta1
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.