Evidence map›Paper›PMID 34426487›Full record

ArticleEuropean journal of hospital pharmacy : science and practice2023

Medical management of first trimester miscarriage: a quality improvement initiative.

Deirdre Hayes-Ryan, Sharon Cooley, Brian Cleary

Open access · greenAbstract read
In one paragraph

Article in European journal of hospital pharmacy : science and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Deirdre Hayes-RyanEarly Pregnancy Unit, Rotunda Hospital, Dublin, Ireland deirdre.hayesryan@hse.ie.ORCID 0000-0003-2490-3661
Sharon CooleyEarly Pregnancy Unit, Rotunda Hospital, Dublin, Ireland.
Brian ClearySchool of Pharmacy, Royal College of Surgeons in Ireland, Dublin, Ireland.
Rotunda Hospital · IERoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMedical management of first trimester pregnancy loss is a safe option that is well tolerated and affords women more autonomy in relation to their care. Recent trials provide robust evidence that mifepristone pretreatment is the optimal approach for women with missed miscarriage who desire medical management.

methodsFollowing a change in medical management of first trimester miscarriage in our unit, we conducted a retrospective audit over a 3-month period of all women who had elected medical management as their primary treatment option. We compared the results with a previous audit that had been undertaken prior to the change in practice.

resultsThe implementation of mifepristone resulted in an increased effectiveness of primary medical treatment for first trimester miscarriage from 53.8% to 85.2% (p=<0.001). DISCUSSION: The results of our study support the introduction of mifepristone into routine clinical practice for medical management of first trimester pregnancy loss across all maternity units.

Indexed as

Abortion, SpontaneousMisoprostolFemaleHumansMifepristonePregnancyPregnancy Trimester, FirstQuality ImprovementRetrospective StudiesMifepristoneMisoprostolclinical medicineevidence-based medicinegynaecologyhealth carehospitalpharmacy servicequality assurance

Identifiers

PMID34426487
PMCPMC10800240
OpenAlexW3193335605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.