Evidence map›Paper›PMID 34426414›Full record

SynthesisCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021

Disparities in Healthcare Providers' Recommendation of HPV Vaccination for U.S. Adolescents: A Systematic Review.

Wei Yi Kong, Gabriela Bustamante, Isabella K Pallotto, Marjorie A Margolis, Rebecca Carlson, Annie-Laurie McRee, Melissa B Gilkey

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Identifying Healthcare Professionals With Lower Human Papillomavirus (HPV) Vaccine Recommendation Quality: A Systematic Review.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Pooled it
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  9. An Analysis of Dental Hygienists' Practices and Perceptions Toward HPV Vaccination.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
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  18. Human Papillomavirus: A Narrative Review for Dental Providers in Prevention and Care.International journal of environmental research and public health · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wei Yi KongGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Gabriela BustamanteMedical School, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-2227-7209
Isabella K PallottoGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Marjorie A MargolisGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Rebecca CarlsonHealth Sciences Library, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-4380-8435
Annie-Laurie McReeMedical School, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0001-6588-5995
Melissa B GilkeyGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. gilkey@email.unc.edu.
University of North Carolina at Chapel Hill · USUniversity of Minnesota · US

Funding

Cancer Control Education ProgramT32CA057726 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa B Gilkey, Melissa A. Troester · 2017 to 2026
$3.7M
Cancer Related Health Disparities Training ProgramT32CA163184 · NCI · UNIVERSITY OF MINNESOTA · PI MICHELE L ALLEN, Irina Stepanov · 2016 to 2026
$3.4M
Evaluating the Feasibility of a Mobile Coaching Intervention to Improve HPV Vaccine DeliveryR21CA241518 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GILKEY, MELISSA B · 2019 to 2020
$399k
NCI NIH HHS R21 CA241518NCI NIH HHS T32 CA057726NCI NIH HHS T32 CA163184
6 · The paper itself

Abstract

Infrequent provider recommendations continue to be a key barrier to human papillomavirus (HPV) vaccination, including among adolescents at higher risk for future HPV cancers. To inform future interventions, we sought to characterize disparities in health care providers' HPV vaccine recommendation for U.S. adolescents. We systematically reviewed studies published in 2012-2019 that assessed provider HPV vaccine recommendations for adolescents aged 9-17. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we identified 52 eligible studies and used a standardized abstraction form to assess recommendation prevalence by adolescent demographic characteristics. Studies consistently found that fewer parents of boys than girls reported receiving HPV vaccine recommendations (14 studies, range of difference: -11 to -35 percentage points). Studies also found fewer recommendations for adolescents who were younger (2 studies, -3% to -12% points), non-White (3 studies, -5% to -7% points, females only), lower income (3 studies, -1% to -8% points), or uninsured (1 study, -21% points, males only). Studies identified geographic disparities in southern and rural areas. In conclusion, findings from this systematic review identify disparities in HPV vaccine recommendation that may contribute to suboptimal vaccine uptake. Efforts to improve providers' HPV vaccine communication should focus on increasing recommendation consistency, especially for lower-income, non-White, and rural adolescents.

Indexed as

Attitude of Health PersonnelAdolescentChildFemaleHealthcare DisparitiesHumansMalePapillomavirus InfectionsPapillomavirus VaccinesParentsPractice Patterns, Physicians'Sex DistributionUnited StatesPapillomavirus Vaccines

Identifiers

PMID34426414
PMCPMC8568647
OpenAlexW3193322956

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.