Evidence map›Paper›PMID 34426041›Full record

ArticleMedical dosimetry : official journal of the American Association of Medical Dosimetrists

A Planning Comparison of IMRT vs. Pencil Beam Scanning for Deep Inspiration Breath Hold Lung Cancers.

Dennis Mah, Ellen Yorke, Entela Zemanaj, Zhiqiang Han, Haoyang Liu, Jobin George, Jason Lambiase, Christian Czmielewski, D Michael Lovelock, Andreas Rimner and 1 more

Open access · greenAbstract read
In one paragraph

Article in Medical dosimetry : official journal of the American Association of Medical Dosimetrists. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. The Future of Radioactive Medicine.Radiation research · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Dennis MahDepartment of Medical Physics, ProCure Proton Therapy Center, Somerset NJ 08873, USA. Electronic address: dennis.mah@procure.com.
Ellen YorkeDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Entela ZemanajDepartment of Medical Physics, ProCure Proton Therapy Center, Somerset NJ 08873, USA.
Zhiqiang HanDepartment of Medical Physics, ProCure Proton Therapy Center, Somerset NJ 08873, USA.
Haoyang LiuDepartment of Medical Physics, ProCure Proton Therapy Center, Somerset NJ 08873, USA.
Jobin GeorgeDepartment of Medical Physics, ProCure Proton Therapy Center, Somerset NJ 08873, USA.
Jason LambiaseDepartment of Medical Physics, ProCure Proton Therapy Center, Somerset NJ 08873, USA.
Christian CzmielewskiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
D Michael LovelockDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Andreas RimnerDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Annemarie F ShepherdDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
ProCure (United States) · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Deep inspiration breath hold (DIBH) has dosimetric advantages for lung cancer patients treated with external beam therapy, but is difficult for many patients to perform. Proton therapy permits sparing of the downstream organs at risk (OAR). We compared conventionally fractionated proton (p) and photon(x) plans on both free breathing (FB) and DIBH planning CTs to determine the effect of DIBH with proton therapy. We evaluated 24 plans from 6 lung cancer patients treated with photon DIBH on a prospective protocol. All patients were re-planned using pencil beam scanning (PBS) proton therapy. New plans were generated for FB datasets with both modalities. All plans were renormalized to 60 Gy. We evaluated dosimetric parameters for heart, lung and esophagus. We also compared FB

Indexed as

Lung NeoplasmsProton TherapyRadiotherapy, Intensity-ModulatedBreath HoldingHeartHumansLungOrgans at RiskProspective StudiesRadiotherapy DosageRadiotherapy Planning, Computer-AssistedDeep inspiration breath holdLung cancerPlanning comparisonProton therapy

Identifiers

PMID34426041
PMCPMC9423111
OpenAlexW3196027805

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.