ArticleVirology journal2021
Genetic diversity and epidemiology of human rhinovirus among children with severe acute respiratory tract infection in Guangzhou, China.
Article in Virology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 27 citations in OpenAlex.
- Molecular epidemiology of human rhinovirus in coastal China: genotyping and epidemic trends in Daishan (2022-2023).Virus genes · 2026Article
- Development and validation of an early warning score for refractoryTranslational pediatrics · 2026Article
- Molecular Types of Rhinovirus Among Cases of Acute Respiratory Infections in a University Hospital.Journal of medical virology · 2026Article
- Age-Related Asymptomatic Rhinovirus Infections Contribute to the Sustained Prevalence in Adults and Are Not Mitigated by Nonpharmaceutical Interventions.Influenza and other respiratory viruses · 2026Article
- No evidence of zoonotic viruses in selected captive and wild-caught grasscutters (Thryonomys swinderianus) in the ashanti region of ghana: a cross-sectional study.BMC veterinary research · 2026Article
- Research progress on the current status of respiratory pathogen infections and their detection methods.Frontiers in microbiology · 2026Review
- Analysis of pediatric respiratory virus epidemiology and its association with atmospheric parameters in Chengdu.Translational pediatrics · 2025Article
- Epidemiology and clinical characteristics of human rhinovirus in hospitalized children and adolescents with acute respiratory infections: a longitudinal study in Shenzhen, China (2019-2024).Virology journal · 2025Article
- Epidemiology and genotypic diversity of rhinovirus in school-age children with acute respiratory illnesses seeking medical care.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2025Article
- In Vitro Characterization of the Immune Response to an Epitope Ensemble Vaccine Against Rhinovirus in Pediatric Asthma and Adults With Chronic Obstructive Pulmonary Disease: Protocol for an Observational and Exploratory Study.JMIR research protocols · 2025Article
- Clinical characteristics, outcomes, and subtype diversity in hospitalized human rhinovirus (HRV) patients.PloS one · 2025Article
- Viral metagenomics reveals diverse viruses in the fecal samples of children with acute respiratory infection.Frontiers in microbiology · 2025Article
- Respiratory pathogen dynamics in community fever cases: Jiangsu Province, China (2023-2024).Virology journal · 2024Article
- Frequent detection and genotyping of human rhinovirus in SARS-CoV-2 negative patients; a study from south of Iran.Iranian journal of microbiology · 2023Article
- Genotypic Diversity of Childhood Rhinovirus Infections.Journal of the Pediatric Infectious Diseases Society · 2023Article
- Phylogenetic characterization of rhinovirus and adenovirus in hospitalized children aged ≤ 18 years with severe acute respiratory infection in Iran.Iranian journal of microbiology · 2023Article
- Article
- Different Clinical Presentations of Human Rhinovirus Species Infection in Children and Adults in Mexico.Open forum infectious diseases · 2022Article
- Molecular epidemiology and clinical characterization of human rhinoviruses circulating in Shanghai, 2012-2020.Archives of virology · 2022Article
- Review
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman rhinovirus (HRV) is one of the major viruses of acute respiratory tract disease among infants and young children. This work aimed to understand the epidemiological and phylogenetic features of HRV in Guangzhou, China. In addition, the clinical characteristics of hospitalized children infected with different subtype of HRV was investigated.
methodsHospitalized children aged < 14 years old with acute respiratory tract infections were enrolled from August 2018 to December 2019. HRV was screened for by a real-time reverse-transcription PCR targeting the viral 5'UTR.
resultsHRV was detected in 6.41% of the 655 specimens. HRV infection was frequently observed in children under 2 years old (57.13%). HRV-A and HRV-C were detected in 18 (45%) and 22 (55%) specimens. All 40 HRV strains detected were classified into 29 genotypes. The molecular evolutionary rate of HRV-C was estimated to be 3.34 × 10
conclusionThis study revealed the molecular epidemiological characteristics of HRV in patients with respiratory infections in southern China. Children infected with HRV-C caused more severe disease characteristics than HRV-A, which might be connected with higher viral load in patients infected with HRV-C. These findings will provide valuable information for the pathogenic mechanism and treatment of HRV infection.
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