Evidence map›Paper›PMID 34425703›Full record

ArticlemBio2021

Protospacer-Adjacent Motif Specificity during Clostridioides difficile Type I-B CRISPR-Cas Interference and Adaptation.

Anna Maikova, Pierre Boudry, Anna Shiriaeva, Aleksandra Vasileva, Anaïs Boutserin, Sofia Medvedeva, Ekaterina Semenova, Konstantin Severinov, Olga Soutourina

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Global insights into the genome dynamics ofFrontiers in cellular and infection microbiology · 2024
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Anna MaikovaCenter of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia.
Pierre BoudryUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Anna ShiriaevaCenter of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia.
Aleksandra VasilevaInstitute of Gene Biology, Centre for Precision Genome Editing and Genetic Technologies for Biomedicine, Russian Academy of Sciences, Moscow, Russia.
Anaïs BoutserinUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Sofia MedvedevaCenter of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia.
Ekaterina SemenovaWaksman Institute of Microbiology, Rutgers, The State University of New Jerseygrid.430387.b, Piscataway, New Jersey, USA.
Konstantin SeverinovCenter of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia.
Olga SoutourinaUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Centre National de la Recherche Scientifique · FRSkolkovo Institute of Science and Technology · RURutgers, The State University of New Jersey · USInstitute of Gene Biology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CRISPR (

Indexed as

CRISPR-Cas SystemsGenome, BacterialAdaptation, PhysiologicalClostridioides difficileCRISPR-Associated ProteinsDNA, BacterialGene EditingCRISPR-Associated ProteinsDNA, BacterialClostridium difficileCRISPR-Cas adaptationCRISPR-Cas interferenceenteropathogenPAMtype I-B CRISPR-Cas

Identifiers

PMID34425703
PMCPMC8406132
OpenAlexW3194918562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.