Evidence map›Paper›PMID 34425696›Full record

ArticlemBio2021

Caspases Switch off the m

Kun Zhang, Yucheng Zhang, Yunash Maharjan, Febri Gunawan Sugiokto, Jun Wan, Renfeng Li

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. WTAP-mediated mScience China. Life sciences · 2025
    Article
  8. Epitranscriptomic sculpting: the role of mMedical oncology (Northwood, London, England) · 2025
    Review
  9. Article
  10. Review
  11. The role of NJournal of virology · 2025
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Recent insights into NCurrent opinion in genetics & development · 2024
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kun ZhangPhilips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth Universitygrid.224260.0, Richmond, Virginia, USA.
Yucheng ZhangDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Yunash MaharjanPhilips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth Universitygrid.224260.0, Richmond, Virginia, USA.
Febri Gunawan SugioktoPhilips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth Universitygrid.224260.0, Richmond, Virginia, USA.
Jun WanDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Renfeng LiPhilips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth Universitygrid.224260.0, Richmond, Virginia, USA.
Virginia Commonwealth University · USIndiana University School of Medicine

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Sara K Quinney · 1999 to 2026
$59.3M
Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0M
The Role of PIAS1 in EBV BiologyR01AI141410 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI LI, RENFENG · 2019 to 2023
$1.9M
Impact of herpesvirus protein kinases on host protein modificationR00AI104828 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI LI, RENFENG · 2014 to 2015
$490k
Impact of herpesvirus protein kinases on host protein modificationK99AI104828 · NIAID · JOHNS HOPKINS UNIVERSITY · PI LI, RENFENG · 2013 to 2013
$85k
NCI NIH HHS P30 CA016059NCI NIH HHS P30 CA082709NIAID NIH HHS K99 AI104828NIAID NIH HHS R00 AI104828NIAID NIH HHS R01 AI141410
6 · The paper itself

Abstract

The methylation of RNA at the N6 position of adenosine (m

Indexed as

RNA Processing, Post-TranscriptionalAdenosineCaspasesCell LineEpstein-Barr Virus InfectionsHerpesvirus 4, HumanHumansMethylationOncogenic VirusesRNA, MessengerVirus ReplicationAdenosineCaspasesRNA, Messengercaspase cleavageEpstein-Barr viruslytic replicationm6A RNA modificationMETTL14METTL3reactivationrestriction factorWTAPYTHDF2

Identifiers

PMID34425696
PMCPMC8406275
OpenAlexW3195522229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.