Trial reportStatistics in medicine2021
The statistical properties of RCTs and a proposal for shrinkage.
Trial report in Statistics in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- INTEGRATE pooled phase 2/3 results are robust to postprogression switching and the winner's curse.JNCI cancer spectrum · 2025Trial
- The statistical properties of RCTs and a proposal for shrinkage.Statistics in medicine · 2021Trial
- Statistically significant results from low-power analyses: A comedy of errors.Global epidemiology · 2026Article
- Estimating the historical minimum false-positive risk of statistically significant reported outcomes in anaesthesia and pain medicine.Anaesthesia · 2026Article
- Reproducibility of statistically significant phase III oncology trials: An In Silico meta-epidemiological analysis.European journal of cancer (Oxford, England : 1990) · 2025Article
- Sports Metaresearch: An Emerging Discipline of Sport Science and Medicine.Sports medicine (Auckland, N.Z.) · 2025Review
- A large-scale in silico replication of ecological and evolutionary studies.Nature ecology & evolution · 2024Article
- Evidenced-Based Prior for Estimating the Treatment Effect of Phase III Randomized Trials in Oncology.JCO precision oncology · 2024Article
- Article
- Interpreting frequentist hypothesis tests: insights from Bayesian inference.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- Interpreting Randomized Controlled Trials.Cancers · 2023Review
- A Meta-Research of Randomized Controlled Trials in the Field of Mental Health: Comparing Pharmacological to Non-Pharmacological Interventions from 1955 to 2020.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023Article
- Less is More? First Impressions From COSMIC-313.Cancer investigation · 2023Article
- Fooled by Significance Testing: An Analysis of the LOVIT Vitamin C Trial.The journal of extra-corporeal technology · 2022Article
- How large should the next study be? Predictive power and sample size requirements for replication studies.Statistics in medicine · 2022Article
- Ten simple rules for good research practice.PLoS computational biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We abstract the concept of a randomized controlled trial as a triple
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.