Evidence map›Paper›PMID 34425317›Full record

ArticleMedical image analysis2021

COVID-19 lung infection segmentation with a novel two-stage cross-domain transfer learning framework.

Jiannan Liu, Bo Dong, Shuai Wang, Hui Cui, Deng-Ping Fan, Jiquan Ma, Geng Chen

Abstract read
In one paragraph

Article in Medical image analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  13. COVID-19 lung infection segmentation from chest CT images based on CAPA-ResUNet.International journal of imaging systems and technology · 2023
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  19. Outbreak COVID-19 in Medical Image Processing Using Deep Learning: A State-of-the-Art Review.Archives of computational methods in engineering : state of the art reviews · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiannan LiuDepartment of Computer Science and Technology, Heilongjiang University, Harbin, China.
Bo DongCenter for Brain Imaging Science and Technology, Zhejiang University, Hangzhou, China.
Shuai WangImaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA.
Hui CuiDepartment of Computer Science and Information Technology, La Trobe University, Melbourne, Australia.
Deng-Ping FanCollege of Computer Science, Nankai University, Tianjin, China.
Jiquan MaDepartment of Computer Science and Technology, Heilongjiang University, Harbin, China. Electronic address: majiquan@hlju.edu.cn.
Geng ChenNational Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology, School of Computer Science and Engineering, Northwestern Polytechnical University, Xi'an, China. Electronic address: gengchen@mail.nwpu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the global outbreak of COVID-19 in early 2020, rapid diagnosis of COVID-19 has become the urgent need to control the spread of the epidemic. In clinical settings, lung infection segmentation from computed tomography (CT) images can provide vital information for the quantification and diagnosis of COVID-19. However, accurate infection segmentation is a challenging task due to (i) the low boundary contrast between infections and the surroundings, (ii) large variations of infection regions, and, most importantly, (iii) the shortage of large-scale annotated data. To address these issues, we propose a novel two-stage cross-domain transfer learning framework for the accurate segmentation of COVID-19 lung infections from CT images. Our framework consists of two major technical innovations, including an effective infection segmentation deep learning model, called nCoVSegNet, and a novel two-stage transfer learning strategy. Specifically, our nCoVSegNet conducts effective infection segmentation by taking advantage of attention-aware feature fusion and large receptive fields, aiming to resolve the issues related to low boundary contrast and large infection variations. To alleviate the shortage of the data, the nCoVSegNet is pre-trained using a two-stage cross-domain transfer learning strategy, which makes full use of the knowledge from natural images (i.e., ImageNet) and medical images (i.e., LIDC-IDRI) to boost the final training on CT images with COVID-19 infections. Extensive experiments demonstrate that our framework achieves superior segmentation accuracy and outperforms the cutting-edge models, both quantitatively and qualitatively.

Indexed as

COVID-19HumansLungMachine LearningSARS-CoV-2Tomography, X-Ray ComputedComputed tomographyCOVID-19Lung infection segmentationTransfer learning

Identifiers

PMID34425317
PMCPMC8342869

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.