Evidence map›Paper›PMID 34425091›Full record

Observational studyArchives of physical medicine and rehabilitation2022

Accuracy of an Algorithm in Predicting Upper Limb Functional Capacity in a United States Population.

Jessica Barth, Kimberly J Waddell, Marghuretta D Bland, Catherine E Lang

Erratum issuedOpen access · greenAbstract readObservational Study
In one paragraph

Observational study in Archives of physical medicine and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Observational
  2. Upper Limb Function 3 Months Post-Stroke: How Accurate Are Physiotherapist Predictions?Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jessica BarthProgram in Physical Therapy, Washington University in St. Louis, St. Louis, MO.
Kimberly J WaddellProgram in Physical Therapy, Washington University in St. Louis, St. Louis, MO.
Marghuretta D BlandProgram in Physical Therapy, Washington University in St. Louis, St. Louis, MO; Program in Occupational Therapy, Washington University in St. Louis, St. Louis, MO; Neurology, Washington University in St. Louis, St. Louis, MO.
Catherine E LangProgram in Physical Therapy, Washington University in St. Louis, St. Louis, MO; Program in Occupational Therapy, Washington University in St. Louis, St. Louis, MO; Neurology, Washington University in St. Louis, St. Louis, MO. Electronic address: langc@wustl.edu.
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational Sciences (TL1)TL1TR002344 · NCATS · WASHINGTON UNIVERSITY · PI Jay F. Piccirillo · 2017 to 2026
$8.5M
DOCTORAL TRAINING PROGRAM IN MOVEMENT SCIENCET32HD007434 · NICHD · WASHINGTON UNIVERSITY · PI Michael D Harris, Catherine Lang · 1993 to 2026
$4.2M
Translation of in-clinic Gains to Gains in Daily Life After StrokeR01HD068290 · NICHD · WASHINGTON UNIVERSITY · PI LANG, CATHERINE · 2012 to 2021
$4.0M
Translation of In-Clinic Gains to Gains in Daily LifeR37HD068290 · NICHD · WASHINGTON UNIVERSITY · PI Catherine Lang · 2022 to 2026
$2.7M
NCATS NIH HHS TL1 TR002344NICHD NIH HHS R01 HD068290NICHD NIH HHS R37 HD068290NICHD NIH HHS T32 HD007434
6 · The paper itself

Abstract

objectiveTo determine the accuracy of an algorithm, using clinical measures only, on a sample of persons with first-ever stroke in the United States (US). It was hypothesized that algorithm accuracy would fall in a range of 70%-80%.

designSecondary analysis of prospective, observational, longitudinal cohort; 2 assessments were done: (1) within 48 hours to 1 week poststroke and (2) at 12 weeks poststroke.

settingRecruited from a large acute care hospital and followed over the first 6 months after stroke.

participantsAdults with first-ever stroke (N=49) with paresis of the upper limb (UL) at ≤48 hours who could follow 2-step commands and were expected to return to independent living at 6 months.

interventionNot applicable.

main outcome measuresThe overall accuracy of the algorithm with clinical measures was quantified by comparing predicted (expected) and actual (observed) categories using a correct classification rate.

resultsThe overall accuracy (61%) and weighted κ (62%) were significant. Sensitivity was high for the Excellent (95%) and Poor (81%) algorithm categories. Specificity was high for the Good (82%), Limited (98%), and Poor (95%) categories. Positive predictive value (PPV) was high for Poor (82%) and negative predictive value (NPV) was high for all categories. No differences in participant characteristics were found between those with accurate or inaccurate predictions.

conclusionsThe results of the present study found that use of an algorithm with clinical measures only is better than chance alone (chance=25% for each of the 4 categories) at predicting a category of UL capacity at 3 months post troke. The moderate to high values of sensitivity, specificity, PPV, and NPV demonstrates some clinical utility of the algorithm within health care settings in the US.

Indexed as

AlgorithmsRecovery of FunctionAdultAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedParesisPredictive Value of TestsProspective StudiesStroke RehabilitationUnited StatesUpper ExtremityMultivariate analysisOccupational therapyPhysical therapyRehabilitationStrokeUpper extremity

Identifiers

PMID34425091
PMCPMC10199719
OpenAlexW3193284772

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.