Evidence map›Paper›PMID 34424924›Full record

ArticlePloS one2021

Determinants of hypertension among patients with type 2 diabetes mellitus on follow-up at Tikur Anbessa Specialized Hospital, Addis Ababa: A case-control study.

Kehabtimer Shiferaw Kotiso, Nabiha Degemu, Samson Gebremedhin, Melaku Taye, Adane Petros, Fanuel Belayneh, Deneke Wolde, Dejene Hailu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kehabtimer Shiferaw KotisoDepartment of Public Health, College of Medicine and Health Sciences, Werabe University, Werabe, Ethiopia.ORCID 0000-0002-4195-0243
Nabiha DegemuSchool of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Samson GebremedhinSchool of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Melaku TayeSchool of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-4435-0083
Adane PetrosSchool of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-9272-3841
Fanuel BelaynehSchool of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Deneke WoldeDepartment of Medical Laboratory, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.
Dejene HailuSchool of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Hawassa University · ETAddis Ababa University · ETWachemo University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertension (HTN) in patients with diabetes mellitus (DM) is a common problem that increases the risk of mortality and morbidity, and lowers the quality of life. Despite the disproportionately high burden of HTN in DM patients, determinants for the comorbidity have not been sufficiently explored. Therefore, this study aimed to identify the determinants of HTN among patients with type 2 diabetes mellitus on follow-up at Tikur Anbessa Specialized Hospital. METHODS AND MATERIALS: We conducted a hospital-based unmatched case-control study at Tikur Anbessa Specialized Hospital on 386 randomly selected patients with type 2 diabetes on follow-up (200 cases and 186 controls). We collected data by using a structured interviewer-administered questionnaire and data extraction form. To identify determinants of hypertension, a multivariable binary logistic regression was fitted, and the findings are presented using adjusted odds ratio (AOR) with 95% confidence interval (CI).

resultsThe mean reported age (±SD) of the cases and the controls was 60.3 (±9.9) and 55.3 (±11.3) years, respectively. The eight identified independent determinants of hypertension with AOR [95% CI] were obesity: 2.82 [1.43, 5.57], sedentary activity of ≥4hrs/day: 1.75 [1.10, 2.79], higher stress score: 1.05 [1.01, 1.10], serum creatinine above 1.1 mg/dl: 2.35 [1.13, 4.91], age: 1.05 [1.02, 1.08], being government employee as compared to private workers: 2.18 [1.06, 4.50] and family history of hypertension: 2.11 [1.26, 3.54]. Further, interaction of diabetes duration with insulin use: 1.03 [1.01, 1.07] was also a significant predictor of HTN among DM patients.

conclusionThe finding calls for interventions for mitigating these determinants. Further research is needed to examine the interaction between diabetes duration and insulin use.

Indexed as

Diabetes Mellitus, Type 2HypertensionAdultAgedCase-Control StudiesEthiopiaFemaleFollow-Up StudiesHospitals, SpecialHumansMaleMiddle AgedRisk Factors

Identifiers

PMID34424924
PMCPMC8382175
OpenAlexW3195618198

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.