Evidence map›Paper›PMID 34424919›Full record

Trial reportPloS one2021

Pathways between caregiver body mass index, the home environment, child nutritional status, and development in children with severe acute malnutrition in Malawi.

Allison I Daniel, Mike Bwanali, Eric O Ohuma, Celine Bourdon, Melissa Gladstone, Isabel Potani, Emmie Mbale, Wieger Voskuijl, Meta van den Heuvel, Robert H J Bandsma

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Allison I DanielCentre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-1774-1214
Mike BwanaliThe Childhood Acute Illness & Nutrition (CHAIN) Network, Blantyre, Malawi.
Eric O OhumaLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Celine BourdonTranslational Medicine Program, Hospital for Sick Children, Toronto, Ontario, Canada.
Melissa GladstoneDepartment of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
Isabel PotaniDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-3494-534X
Emmie MbaleThe Childhood Acute Illness & Nutrition (CHAIN) Network, Blantyre, Malawi.
Wieger VoskuijlThe Childhood Acute Illness & Nutrition (CHAIN) Network, Blantyre, Malawi.ORCID 0000-0001-5825-2831
Meta van den HeuvelCentre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada.
Robert H J BandsmaCentre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada.
Hospital for Sick Children · CAUniversity of Malawi · MWUniversity of Toronto · CAEmma Kinderziekenhuis · NLLondon School of Hygiene & Tropical Medicine · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children with severe acute malnutrition (SAM) remain vulnerable after treatment at nutritional rehabilitation units (NRUs). The objective was to assess the concurrent pathways in a hypothesized model between caregiver body mass index (BMI), the home environment, and child nutritional status, and development (gross motor, fine motor, language, and social domains) in children with SAM following discharge from inpatient treatment. Structural equation modelling (SEM) was performed with data from a cluster-randomized controlled trial at the Moyo Nutritional Rehabilitation and Research Unit in Blantyre, Malawi. This approach was undertaken to explore simultaneous relationships between caregiver BMI, the home environment (Home Observation for Measurement of the Environment Inventory scores), child nutritional status (anthropometric indicators including weight-for-age z-scores [WAZ]), and child development (Malawi Developmental Assessment Tool (MDAT) z-scores as a latent variable) in children with SAM. These data were collected at participants' homes six months after discharge from NRU treatment. This analysis included 85 children aged 6-59 months with SAM and their caregivers recruited to the trial at the NRU and followed up successfully six months after discharge. The model with WAZ as the nutritional indicator fit the data according to model fit indices (χ2 = 28.92, p = 0.42). Caregiver BMI was predictive of better home environment scores (β = 0.23, p = 0.03) and child WAZ (β = 0.30, p = 0.005). The home environment scores were positively correlated with MDAT z-scores (β = 0.32, p = 0.001). Child nutritional status based on WAZ was also correlated with MDAT z-scores (β = 0.37, p<0.001). This study demonstrates that caregiver BMI could ultimately relate to child development in children with SAM, through its links to the home environment and child nutritional status.

Indexed as

Body Mass IndexChild DevelopmentChild Nutritional Physiological PhenomenaNutritional StatusAdultCaregiversChild, PreschoolFemaleHome Care ServicesHumansInfantMalawiMaleSevere Acute Malnutrition

Identifiers

PMID34424919
PMCPMC8382172
OpenAlexW3195131359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.