ArticlePLoS neglected tropical diseases2021
Mapping of Ebola virus spillover: Suitability and seasonal variability at the landscape scale.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review of health risk assessment in Africa's bushmeat trade: Are there any risks assessed?PLoS neglected tropical diseases · 2026Pooled it
- Geo-Enabling Public Health: A Systematic Review of GIS Applications.Advances in experimental medicine and biology · 2026Pooled it
- Bioinformatics-driven genome-wide identification of viral miRNAs in high spillover bat coronaviruses and their target genes in human.Archives of microbiology · 2026Article
- Strengthening health systems in lower-middle-income countries (LMICs) in Africa through the WHO Hub for emergency preparedness and outbreak response.One health outlook · 2026Review
- Ebola virus disease: A persistent challenge in global health security.Open veterinary journal · 2026Review
- Article
- High-Resolution Mapping of Environmental Suitability for Reported Ebola Spillover Events in Uganda to Inform Surveillance and Preparedness.Journal of tropical medicine · 2026Article
- Spatial risks of Orthoebolavirus spillover vary based on outbreak type.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025Article
- Assessing the ecological resilience of Ebola virus in Africa and potential influencing factors based on a synthesized model.PLoS neglected tropical diseases · 2025Article
- Spatial examination of social and environmental drivers of Middle East respiratory syndrome coronavirus (MERS-CoV) across Kenya.EcoHealth · 2024Article
- Fruit-frugivore dependencies are important inEcography · 2024Article
- Seasonal Patterns of Mpox Index Cases, Africa, 1970-2021.Emerging infectious diseases · 2024Article
- Evidence of repeated zoonotic pathogen spillover events at ecological boundaries.Frontiers in public health · 2024Article
- Article
- Modeling Supply and Demand Dynamics of Vaccines against Epidemic-Prone Pathogens: Case Study of Ebola Virus Disease.Vaccines · 2023Article
- Robust evidence for bats as reservoir hosts is lacking in most African virus studies: a review and call to optimize sampling and conserve bats.Biology letters · 2023Review
- Article
- Estimation of Ebola's spillover infection exposure in Sierra Leone based on sociodemographic and economic factors.PloS one · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The unexpected Ebola virus outbreak in West Africa in 2014 involving the Zaire ebolavirus made clear that other regions outside Central Africa, its previously documented niche, were at risk of future epidemics. The complex transmission cycle and a lack of epidemiological data make mapping areas at risk of the disease challenging. We used a Geographic Information System-based multicriteria evaluation (GIS-MCE), a knowledge-based approach, to identify areas suitable for Ebola virus spillover to humans in regions of Guinea, Congo and Gabon where Ebola viruses already emerged. We identified environmental, climatic and anthropogenic risk factors and potential hosts from a literature review. Geographical data layers, representing risk factors, were combined to produce suitability maps of Ebola virus spillover at the landscape scale. Our maps show high spatial and temporal variability in the suitability for Ebola virus spillover at a fine regional scale. Reported spillover events fell in areas of intermediate to high suitability in our maps, and a sensitivity analysis showed that the maps produced were robust. There are still important gaps in our knowledge about what factors are associated with the risk of Ebola virus spillover. As more information becomes available, maps produced using the GIS-MCE approach can be easily updated to improve surveillance and the prevention of future outbreaks.
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