Evidence map›Paper›PMID 34424758›Full record

Observational studyHigh altitude medicine & biology2021

A Breathtaking Lift: Sex and Body Mass Index Differences in Cardiopulmonary Response in a Large Cohort of Unselected Subjects with Acute Exposure to High Altitude.

Carlo Vignati, Massimo Mapelli, Benedetta Nusca, Alice Bonomi, Elisabetta Salvioni, Irene Mattavelli, Susanna Sciomer, Andrea Faini, Gianfranco Parati, Piergiuseppe Agostoni

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in High altitude medicine & biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Partial pressure of oxygen-guided adrenal venous sampling in primary aldosteronism.The Journal of clinical endocrinology and metabolism · 2026
    Article
  2. Article
  3. Reframing SpOFrontiers in physiology · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Carlo VignatiCentro Cardiologico Monzino, IRCCS, Milan, Italy.ORCID 0000-0002-8235-9353
Massimo MapelliCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Benedetta NuscaCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Alice BonomiCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Elisabetta SalvioniCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Irene MattavelliCentro Cardiologico Monzino, IRCCS, Milan, Italy.
Susanna SciomerDipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, "Sapienza" Rome University, Rome, Italy.
Andrea FainiIstituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy.
Gianfranco ParatiIstituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy.
Piergiuseppe AgostoniCentro Cardiologico Monzino, IRCCS, Milan, Italy.ORCID 0000-0002-8345-6382
Centro Cardiologico Monzino · ITUniversity of Milan · ITIRCCS Istituto Auxologico Italiano · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vignati, Carlo, Massimo Mapelli, Benedetta Nusca, Alice Bonomi, Elisabetta Salvioni, Irene Mattavelli, Susanna Sciomer, Andrea Faini, Gianfranco Parati, and Piergiuseppe Agostoni. A breathtaking lift: sex and body mass index differences in cardiopulmonary response in a large cohort of unselected subjects with acute exposure to high altitude.

Indexed as

AltitudeAltitude SicknessAdultAgedBody Mass IndexHumansHypoxiaMaleMiddle AgedOxygenOxygen SaturationYoung AdultOxygenacute hypoxiaBMIhigh altitudesex differences

Identifiers

PMID34424758
PMCPMC8742268
OpenAlexW3195335079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.