Evidence map›Paper›PMID 34424538›Full record

ArticleCancer2021

Cut points and contexts.

Evan L Busch

Abstract read
In one paragraph

Article in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Straining Under Contradiction? Contradictory Class Locations and Job Strain in the United States.International journal of social determinants of health and health services · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Health-Related Physical Fitness Evaluation in HIV-Diagnosed Children and Adolescents: A Scoping Review.International journal of environmental research and public health · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Evan L BuschDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.ORCID 0000-0001-6829-6846

Funding

Training Program in Cancer EpidemiologyT32CA009001 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI A. Heather Eliassen, Meir Stampfer · 1985 to 2026
$17.3M
NCI NIH HHS 5T32CA009001NCI NIH HHS T32 CA009001
6 · The paper itself

Abstract

In research, policy, and practice, continuous variables are often categorized. Statisticians have generally advised against categorization for many reasons, such as loss of information and precision as well as distortion of estimated statistics. Here, a different kind of problem with categorization is considered: the idea that, for a given continuous variable, there is a unique set of cut points that is the objectively correct or best categorization. It is shown that this is unlikely to be the case because categorized variables typically exist in webs of statistical relationships with other variables. The choice of cut points for a categorized variable can influence the values of many statistics relating that variable to others. This essay explores the substantive trade-offs that can arise between different possible cut points to categorize a continuous variable, making it difficult to say that any particular categorization is objectively best. Limitations of different approaches to selecting cut points are discussed. Contextual trade-offs may often be an argument against categorization. At the very least, such trade-offs mean that research inferences, or decisions about policy or practice, that involve categorized variables should be framed and acted upon with flexibility and humility. LAY SUMMARY: In research, policy, and practice, continuous variables are often turned into categorical variables with cut points that define the boundaries between categories. This involves choices about how many categories to create and what cut-point values to use. This commentary shows that different choices about which cut points to use can lead to different sets of trade-offs across multiple statistical relationships between the categorized variable and other variables. These trade-offs mean that no single categorization is objectively best or correct. This context is critical when one is deciding whether and how to categorize a continuous variable.

Indexed as

data analysisstatistical data interpretationstatisticstranslational medical researchtranslational medical science

Identifiers

PMID34424538
PMCPMC8578203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.