ArticleEnvironmental science and pollution research international2022
Attributes of oxidative stress in the reproductive toxicity of nickel oxide nanoparticles in male rats.
Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Resveratrol regulates nickel oxide-induced kidney damage by targeting the PERK/ATF-6/IRE1 and Nrf2/HO1 pathways.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Mechanistic paradigms of teratogenicity induced by metallic nanoparticles-a mini review.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Review
- Promoting Drp1-Mediated Mitochondrial Division in Nickel Nanoparticles-Induced Reproductive Toxicity in GC-2 Cells.Nanomaterials (Basel, Switzerland) · 2025Article
- Effect of High-Intensity Interval Training on Mitigating High-Fat Diet-Induced Damage in Rat Testicular Tissue.Preventive nutrition and food science · 2025Article
- Nickel-based nanomaterials: a comprehensive analysis of risk assessment, toxicity mechanisms, and future strategies for health risk prevention.Journal of nanobiotechnology · 2025Review
- Article
- Susceptibility of Human Spermatozoa to Titanium Dioxide Nanoparticles: Evaluation of DNA Damage and Biomarkers.Life (Basel, Switzerland) · 2024Article
- The pulmonary effects of nickel-containing nanoparticles: Cytotoxicity, genotoxicity, carcinogenicity, and their underlying mechanisms.Environmental science. Nano · 2024Article
- Nickel oxide nanoparticles exposure as a risk factor for male infertility: "Frontiers in endocrinology · 2023Article
- Association between urinary nickel with obesity status in adults: A cross-sectional study.Frontiers in public health · 2023Article
- Allethrin Promotes Apoptosis and Autophagy Associated with the Oxidative Stress-Related PI3K/AKT/mTOR Signaling Pathway in Developing Rat Ovaries.International journal of molecular sciences · 2022Article
- Cytotoxicity of Metal-Based Nanoparticles: From Mechanisms and Methods of Evaluation to Pathological Manifestations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nanoparticles of nickel are now being widely used in industrial, commercial, and biomedical applications. In recent years, health safety issues posed by them have aroused concerns among health scientists. The aim of the present study was to investigate the role of oxidative stress in male reproductive toxicity induced by nickel oxide nanoparticles in rats. Male Wistar rats (140-170 g) were administered with nickel oxide nanoparticles (NiONPs) (particles size <30 nm) (5 mg/kg body weight) by gavage for 30 days. Its effects on different parameters, viz., sperm count, motility, and morphology, were investigated. DNA damage in sperms was monitored through comet assay. All these observations indicated a spermicidal effect of NiONPs. Results on lipid peroxidation (MDA, H
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