Evidence map›Paper›PMID 34424451›Full record

ReviewClinical and experimental medicine2022

COVID-19-associated opportunistic infections: a snapshot on the current reports.

Amir Abdoli, Shahab Falahi, Azra Kenarkoohi

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 3 pooled it
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 3 syntheses or guidelines pooled it, 148 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Article
  10. A Comparative Analysis of COVID-19-Associated and Non-COVID-19-Associated MucormycosisEndocrine, metabolic & immune disorders drug targets · 2026
    Article
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  13. Promising Prodiginins Biological Activities.Chemistry & biodiversity · 2025
    Review
  14. Article
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  18. Selective phosphodiesterase 4 inhibitor roflumilast reduces inflammation and lung injury in models of betacoronavirus infection in mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  19. Review
  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amir AbdoliZoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran. a.abdoli25@gmail.com.ORCID http://orcid.org/0000-0003-4326-4586
Shahab FalahiZoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Azra KenarkoohiDepartment of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Medical University of Ilam · IRJahrom University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of the novel Coronavirus Disease 2019 (COVID-19) remains a complicated challenge, especially among patients with severe disease. In recent studies, immunosuppressive therapy has shown promising results for control of the cytokine storm syndrome (CSS) in severe cases of COVID-19. However, it is well documented that immunosuppressive agents (e.g., corticosteroids and cytokine blockers) increase the risk of opportunistic infections. On the other hand, several opportunistic infections were reported in COVID-19 patients, including Aspergillus spp., Candida spp., Cryptococcus neoformans, Pneumocystis jiroveci (carinii), mucormycosis, Cytomegalovirus (CMV), Herpes simplex virus (HSV), Strongyloides stercoralis, Mycobacterium tuberculosis, and Toxoplasma gondii. This review is a snapshot about the main opportunistic infections that reported among COVID-19 patients. As such, we summarized information about the main immunosuppressive agents that were used in recent clinical trials for COVID-19 patients and the risk of opportunistic infections following these treatments. We also discussed about the main challenges regarding diagnosis and treatment of COVID-19-associated opportunistic infections (CAOIs).

Indexed as

CandidiasisCOVID-19COVID-19 Drug TreatmentCytomegalovirus InfectionsOpportunistic InfectionsPneumonia, PneumocystisHumansImmunosuppressive AgentsImmunosuppressive AgentsAspergillosisCandidiasisCOVID-19CryptococcosisCytokine storm syndromeCytomegalovirusHelminth infectionsHerpes simplex virusImmunosuppressive therapyMucormycosisOpportunistic infectionPneumocystis jirovecii pneumoniaSARS-CoV-2StrongyloidiasisToxoplasmosisTuberculosis

Identifiers

PMID34424451
PMCPMC8381864
OpenAlexW3195174714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.