Evidence map›Paper›PMID 34424198›Full record

ArticleeLife2021

An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface.

Pooja Pandey, Alexandre Y Leary, Yasin Tumtas, Zachary Savage, Bayantes Dagvadorj, Cian Duggan, Enoch Lh Yuen, Nattapong Sanguankiattichai, Emily Tan, Virendrasinh Khandare and 8 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 70 citations in OpenAlex.

  1. Review
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Autophagy in plants.Autophagy reports · 2024
    Review
  15. Article
  16. Fungal Effectoromics: A World in Constant Evolution.International journal of molecular sciences · 2022
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Pooja Pandey *Imperial College London, London, United Kingdom.ORCID 0000-0003-3145-7794
Alexandre Y Leary *Imperial College London, London, United Kingdom.ORCID 0000-0001-7223-3557
Yasin TumtasImperial College London, London, United Kingdom.
Zachary SavageImperial College London, London, United Kingdom.
Bayantes DagvadorjImperial College London, London, United Kingdom.ORCID 0000-0002-0188-9353
Cian DugganImperial College London, London, United Kingdom.ORCID 0000-0001-7302-7472
Enoch Lh YuenImperial College London, London, United Kingdom.ORCID 0000-0002-7933-0605
Nattapong SanguankiattichaiImperial College London, London, United Kingdom.
Emily TanImperial College London, London, United Kingdom.
Virendrasinh KhandareImperial College London, London, United Kingdom.ORCID 0000-0003-2673-6561
Amber J ConnertonImperial College London, London, United Kingdom.
Temur YunusovSainsbury Laboratory Cambridge University (SLCU), Cambridge, United Kingdom.
Mathias MadalinskiGregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria.
Federico Gabriel MirkinImperial College London, London, United Kingdom.
Sebastian SchornackSainsbury Laboratory Cambridge University (SLCU), Cambridge, United Kingdom.ORCID 0000-0002-7836-5881
Yasin DagdasGregor Mendel Institute (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-9502-355X
Sophien KamounThe Sainsbury Laboratory, University of East Anglia, Norwich, United Kingdom.ORCID 0000-0002-0290-0315
Tolga O BozkurtImperial College London, London, United Kingdom.ORCID 0000-0003-0507-6875
Imperial College London · GBGregor Mendel Institute of Molecular Plant Biology · ATUniversity of Cambridge · GBUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M002462/1Biotechnology and Biological Sciences Research Council BB/M011224/1Biotechnology and Biological Sciences Research Council BBS/E/J 000PR9797
6 · The paper itself

Abstract

Eukaryotic cells deploy autophagy to eliminate invading microbes. In turn, pathogens have evolved effector proteins to counteract antimicrobial autophagy. How adapted pathogens co-opt autophagy for their own benefit is poorly understood. The Irish famine pathogen

Indexed as

Host-Pathogen InteractionsAutophagyFungal ProteinsPhytophthora infestansPlant DiseasesPlant ProteinsSolanum tuberosumFungal ProteinsPlant Proteinsautophagyautophagy inhibitionhaustoriumnicotiana benthamianaPhytophthora infestansplant biology

Identifiers

PMID34424198
PMCPMC8382295
OpenAlexW3193924706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.