Evidence map›Paper›PMID 34424114›Full record

ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2022

The relationship between teen-reported nocturnal asthma symptoms and daily functioning.

Anne Zhang, Maria Fagnano, Sean M Frey, Jill S Halterman

Abstract read
In one paragraph

Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anne ZhangDepartment of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Maria FagnanoDepartment of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.
Sean M FreyDepartment of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.ORCID 0000-0002-8674-7572
Jill S HaltermanDepartment of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
School-Based Asthma Care for Teens (SB-ACT)R18HL116244 · NHLBI · UNIVERSITY OF ROCHESTER · PI HALTERMAN, JILL S · 2014 to 2018
$3.6M
NHLBI NIH HHS R18 HL116244NIEHS NIH HHS P30 ES001247
6 · The paper itself

Abstract

objectiveThis study aims to identify associations between nocturnal asthma awakenings and functional health outcomes in a cohort of teenagers with asthma.

methodsWe analyzed baseline data from teenagers enrolled in SB-ACT, an NIH-funded RCT. During an at-home baseline survey, teenagers with asthma answered questions about demographics, recent asthma symptoms, and functional health outcomes. We conducted regression analyses to explore the relationship between persistent nocturnal asthma symptoms (≥2 nights of nocturnal asthma awakenings in the past 14 days) and functional health measures.

resultsOf the 430 teens enrolled (Participation rate = 79%, Mean Age = 13.4), 30% reported persistent nocturnal asthma symptoms. Compared to teens with intermittent nocturnal asthma symptoms, teens with persistent nocturnal asthma symptoms were more likely to report physical limitation during strenuous activities (OR = 1.9, 1.3-3.0), moderate activities (OR = 1.9, 1.2-3.1), and school gym (OR = 2.4, 1.5-3.8). They were also more likely to report depressive symptoms (OR = 2.3, 1.5-3.6), more asthma-related school absenteeism in the past 14 days (0.81 vs 0.12, p < 0.01) and poorer quality of life (4.6 vs 5.9, p < 0.01). These findings remained significant when controlling for daytime asthma symptoms, weight status, race, ethnicity, gender, age, and smoke exposure.

conclusionsIn this cross-sectional study, persistent nighttime asthma symptoms were associated with poor functional health outcomes among teens, independent of day-time symptoms. Identifying nighttime symptoms and improving asthma control at night may positively impact daily functioning for these teens.

Indexed as

AsthmaAdolescentCross-Sectional StudiesHumansQuality of LifeSchoolsSurveys and Questionnairesactivity limitationAdolescentsdepressionmanagement/controlpreventionquality of life

Identifiers

PMID34424114
PMCPMC8898318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.