ArticleCirculation research2021
Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration.
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Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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47citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
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Who cites it
47 citing papers in PubMed, 61 citations in OpenAlex.
- [Research progress on the regulatory role and mechanisms of the Hippo signaling pathway in the pathogenesis of congenital heart disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Review
- Signaling pathways regulating cardiac regeneration.Cell regeneration (London, England) · 2026Review
- Loss of ATP-Dependent Citrate Lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling.Circulation · 2026Article
- ERK-Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Fibrosis Process Activation in Patients with Acute Cardiac Rejection: A Novel Noninvasive Diagnostic Approach.Biomedicines · 2026Article
- Zinc finger BED-type containing 6 (ZBED6) ameliorates cardiac fibrosis by inhibiting Piezo1 transcription and YAP nuclear translocation.Acta pharmacologica Sinica · 2026Article
- YAP Induces a Prorenewal Metabolic State in Cardiomyocytes.Circulation · 2026Article
- Decoding organ fibrosis: mechanistic insights and emerging therapeutic strategies.Signal transduction and targeted therapy · 2026Review
- USP16 S-nitrosylation aggravates coronary microembolization-induced myocardial injury via repressing KDM1A-mediated glutathione homeostasis.Nature communications · 2025Article
- Molecular gatekeepers of endogenous adult mammalian cardiomyocyte proliferation.Nature reviews. Cardiology · 2025Review
- Targeting the Hippo Pathway for Cardiac Regeneration.Physiology (Bethesda, Md.) · 2025Review
- Cell type specificity of Hippo-YAP signaling in cardiac development and disease.Journal of molecular and cellular cardiology · 2025Review
- Review
- Article
- Advancements in CRISPR/Cas systems for disease treatment.Acta pharmaceutica Sinica. B · 2025Review
- The effects of YAP/TAZ in cardiomyocytes: a scoping review.Molecular biology reports · 2025Article
- Complex regulation of cardiac fibrosis: insights from immune cells and signaling pathways.Journal of translational medicine · 2025Review
- Molecular Insights into Ischemia-Reperfusion Injury in Coronary Artery Disease: Mechanisms and Therapeutic Implications: A Comprehensive Review.Antioxidants (Basel, Switzerland) · 2025Review
- Spotlight on YAP: Unlocking New Insights to Overcome the Barriers to Heart Regeneration.Circulation · 2025Article
- Phosphoserine aminotransferase 1 promotes serine synthesis pathway and cardiac repair after myocardial infarction.Theranostics · 2025Article
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Authors and funding
9 authors at 6 institutions in 5 countries.
Shijie LiuCardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston (S.L., T.R.H., J.F.M.).ORCID 0000-0002-2597-5416
Li TangDepartment of Molecular Physiology and Biophysics (L.T., B.N., J.F.M.), Baylor College of Medicine, One Baylor Plaza, Houston, TX.
Xiaolei ZhaoDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center, Houston (X.Z., J.W.).ORCID 0000-0002-4697-3874
Bao NguyenDepartment of Molecular Physiology and Biophysics (L.T., B.N., J.F.M.), Baylor College of Medicine, One Baylor Plaza, Houston, TX.
Todd R HeallenCardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston (S.L., T.R.H., J.F.M.).ORCID 0000-0002-6003-8743
Min Li
Jianxin WangSchool of Computer Science and Engineering, Central South University, Changsha, Hunan, China (L.T., Jianxin Wang).
Jun WangDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center, Houston (X.Z., J.W.).
James F MartinCardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston (S.L., T.R.H., J.F.M.).ORCID 0000-0002-7842-9857
Central South University · CNHeart Rhythm Society · USBaylor College of Medicine · USIE University · ESMinistry of Culture · BRThe University of Texas Health Science Center · US
Funding
Pitx2 in atrial fibrillationR01HL118761 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MARTIN, JAMES F · 2014 to 2025
$6.1MHippo and Wnt Signaling in Cardiac RegenerationR01HL127717 · NHLBI · TEXAS HEART INSTITUTE · PI MARTIN, JAMES F · 2016 to 2023
$4.4MGenetic dissection of Cardiac Conduction System homeostasis and RepairR01HL142704 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Jun Wang · 2020 to 2026
$3.0MOptical elastography for assessment of myocardial regenerationR01HL130804 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LARIN, KIRILL V, MARTIN, JAMES F · 2016 to 2019
$2.9MMolecular Regulatory Mechanism of Cranial Neural Crest DevelopmentR01DE029014 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WANG, JUN · 2020 to 2024
$1.8MA Hippo-Yap Pathway in Cranial Bone Development and RegenerationK01DE026561 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WANG, JUN · 2017 to 2021
$739kGenetic dissection of Cardiac Conduction System homeostasis and regenerationR56HL142704 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WANG, JUN · 2018 to 2018
$396ka Yap/Taz mediated signaling crosstalk in cranial bone developmentR03DE025873 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WANG, JUN · 2017 to 2018
$313kNHLBI NIH HHS R01 HL118761NHLBI NIH HHS R01 HL127717NHLBI NIH HHS R01 HL130804NHLBI NIH HHS R01 HL142704NHLBI NIH HHS R56 HL142704NIDCR NIH HHS K01 DE026561NIDCR NIH HHS R01 DE029014NIDCR NIH HHS R03 DE025873
Abstract
[Figure: see text].
Indexed as
RegenerationAnimalsCells, CulturedHumansMiceMice, Inbred C57BLMyocardial InfarctionMyocytes, CardiacMyofibroblastsReceptors, G-Protein-CoupledWnt ProteinsWnt Signaling PathwayYAP-Signaling ProteinsGpr177 protein, mouseReceptors, G-Protein-CoupledWnt ProteinsYap1 protein, mouseYAP-Signaling ProteinsCRISPR-Cas systemsextracellular matrixfibrosismyocardial infarctionWnt signaling pathway
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.