ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2021
The Vitamin D Metabolite Ratio Is Associated With Changes in Bone Density and Fracture Risk in Older Adults.
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Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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26citing papers in PubMed, 1 pooled it
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- B vitamins and bone health: a meta-analysis with trial sequential analysis of randomized controlled trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Pooled it
- Classification of Vitamin D Status Based on Vitamin D Metabolism: A Randomized Controlled Trial in Hypertensive Patients.Nutrients · 2024Trial
- Association of the vitamin D metabolite ratio with bone turnover markers and changes in volumetric BMD.JBMR plus · 2026Article
- Increased Levels of the Vitamin D Metabolite Ratio Are Protective Against Progression From Islet Autoimmunity to T1D.The Journal of clinical endocrinology and metabolism · 2026Article
- Therapeutic Plasma Exchange and Changes in Calcium, Phosphate, Parathyroid Hormone, and Fibroblast Growth Factor-23.The Journal of clinical endocrinology and metabolism · 2026Article
- Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.The Journal of clinical endocrinology and metabolism · 2025 · on this mapArticle
- Investigation of the Vitamin D Metabolite Ratio (VMR) as a Marker of Functional Vitamin D Deficiency: Findings from the SarcoPhAge Cohort.Nutrients · 2024Article
- Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows.Endocrine reviews · 2024Article
- Value of Vitamin D Metabolite Ratios in 3 Patients as Diagnostic Criteria to Assess Vitamin D Status.JCEM case reports · 2024 · on this mapArticle
- Risk factors for hip and vertebral fractures in chronic kidney disease: the CRIC study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.medRxiv : the preprint server for health sciences · 2024Article
- An ultra-sensitive and high-throughput trapping-micro-LC-MS method for quantification of circulating vitamin D metabolites and application in multiple sclerosis patients.Scientific reports · 2024Article
- The Vitamin D Metabolite Ratio Is Associated With Volumetric Bone Density in Older Men.The Journal of clinical endocrinology and metabolism · 2024Article
- Exploring the Paradox of Bone Mineral Density in Type 2 Diabetes: A Comparative Study Using Opportunistic Chest CT Texture Analysis and DXA.Diagnostics (Basel, Switzerland) · 2023Article
- Vitamin D Metabolites and Risk of Cardiovascular Disease in Chronic Kidney Disease: The CRIC Study.Journal of the American Heart Association · 2023Article
- The Vitamin D Metabolite Ratio (VMR) is a Biomarker of Vitamin D Status That is Not Affected by Acute Changes in Vitamin D Binding Protein.Clinical chemistry · 2023Article
- Determination of 24,25-dihydroxyvitamin DThe Journal of steroid biochemistry and molecular biology · 2023Article
- Vitamin D Metabolite Ratio and Coronary Artery Calcification in the Multi-Ethnic Study of Atherosclerosis.Circulation. Cardiovascular imaging · 2023Article
- 24,25-Dihydroxy Vitamin D and Vitamin D Metabolite Ratio as Biomarkers of Vitamin D in Chronic Kidney Disease.Nutrients · 2023Article
- There is a significantly inverse relationship between dietary riboflavin intake and prevalence of osteoporosis in women but not in men: Results from the TCLSIH cohort study.Frontiers in nutrition · 2023Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Charles GinsbergDivision of Nephrology-Hypertension, University of California San Diego, San Diego, CA, USA.ORCID 0000-0001-9408-3684
Andrew N HoofnagleDepartments of Laboratory Medicine and Medicine and the Kidney Research Institute, University of Washington, Seattle, WA, USA.
Ronit KatzDepartment of Obstetrics and Gynecology, University of Washington, Seattle, WA, USA.
Jan Hughes-AustinDepartments of Laboratory Medicine and Medicine and the Kidney Research Institute, University of Washington, Seattle, WA, USA.ORCID 0000-0002-7255-274X
Lindsay M MillerDepartments of Laboratory Medicine and Medicine and the Kidney Research Institute, University of Washington, Seattle, WA, USA.
Jessica O BeckerDepartments of Laboratory Medicine and Medicine and the Kidney Research Institute, University of Washington, Seattle, WA, USA.
Stephen B KritchevskyDepartment of Internal Medicine, Section of Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Michael G ShlipakKidney Health Research Collaborative, Veterans Affairs Medical Center, San Francisco, CA, USA.
Mark J SarnakDepartment of Medicine, Division of Nephrology, Tufts Medical Center, Boston, MA, USA.
Joachim H IxDepartments of Laboratory Medicine and Medicine and the Kidney Research Institute, University of Washington, Seattle, WA, USA.
University of Washington · USSan Francisco VA Medical Center · USTufts Medical Center · USUniversity of California San Diego · USWake Forest University · US
Funding
PILOT STUDY--CLINICAL NUTRITION RESEARCHP30DK035816 · NIDDK · UNIVERSITY OF WASHINGTON · PI Ellen A Schur · 1986 to 2026
$30.4MThe Aging Kidney: Chronic Injury, Impaired Functions and Clinical OutcomesR01AG027002 · NIA · TUFTS MEDICAL CENTER · PI PARIKH, SAMIR M, SARNAK, MARK J · 2005 to 2022
$7.3MIntentional weight reduction and physical and cognitive functionR01AG033087 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KRITCHEVSKY, STEPHEN B. · 2009 to 2013
$4.0MPeripheral Nerve Function Decline in an Aged CohortR01AG028050 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 2007 to 2015
$3.5MEnd of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7MEffects of Niacin on Mineral Metabolism in Chronic Kidney DiseaseR01DK101720 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI IX, JOACHIM H · 2014 to 2016
$1.2MInfluence of Vitamin D Binding Protein on Clinical Measures of Vitamin D Status and Bone HealthK23DK118197 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GINSBERG, CHARLES · 2018 to 2022
$1.0MDYNAMICS OF HEALTH .AGING . AND BODY COMPOSITION /Pittsburgh/-260962101N01AG062101 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1996 to 2004
$996kDYNAMICS OF HEALTH . AGING . AND BODY COMPOSITION /Memphis/-26062103N01AG062103 · NIA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · 1996 to 2004
$793kMentored Patient Oriented Research in Kidney DiseaseK24DK110427 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI IX, JOACHIM H · 2016 to 2020
$780kHEALTH ABC--COORDINATING UNIT /California/-260062106N01AG062106 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · 1996 to 2004
$109kAmerican Heart Association-American Stroke Association 14EIA18560026NIA NIH HHS 5R01AG027002NIA NIH HHS N01-AG-6-2101NIA NIH HHS N01-AG-6-2103NIA NIH HHS N01-AG-6-2106NIA NIH HHS R01 AG027002NIA NIH HHS R01 AG028050NIA NIH HHS R01AG028050NIA NIH HHS R01 AG033087NIA NIH HHS R01AG033087NIDDK NIH HHS K23 DK118197NIDDK NIH HHS K23DK118197NIDDK NIH HHS K24 DK110427NIDDK NIH HHS K24DK110427NIDDK NIH HHS P30 DK035816NIDDK NIH HHS R01 DK101720NIDDK NIH HHS R01DK101720NIH HHS P30DK035816NINR NIH HHS R01 NR012459NINR NIH HHS R01NR012459
Abstract
Recent studies have suggested that 25-hydroxyvitamin D (25(OH)D) may be a poor biomarker of bone health, in part because measured levels incorporate both protein-bound and free vitamin D. The ratio of its catabolic product (24,25-dihydroxyvitamin D [24,25(OH)
Indexed as
Bone DensityFractures, BoneAgedCalcifediolFemaleHumansRetrospective StudiesVitamin DCalcifediolVitamin DDXAFRACTURE PREVENTIONOSTEOPOROSISPTH/VITAMIN D/FGF23
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.