Evidence map›Paper›PMID 34423732›Full record

ArticleOphthalmic epidemiology2023

Trachoma Prevalence in Four Localities of Darfur Region, Sudan, following One Round of Antibiotic Mass Drug Administration.

Balgesa E Elshafie, Mazin Salih Abdalla Elsanosi, Atif El Amin, Robert Butcher, Rebecca Willis, Ana Bakhtiari, Cristina Jimenez, Michael Dejene, Anthony W Solomon, Emma M Harding-Esch and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Ophthalmic epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Balgesa E ElshafieSudan National Trachoma Control Programme, Khartoum, Sudan.
Mazin Salih Abdalla ElsanosiThe Carter Center, Khartoum, Sudan.
Atif El AminSudan National Trachoma Control Programme, Khartoum, Sudan.
Robert ButcherClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
Rebecca WillisTaskforce for Global Health, Atlanta, Georgia, USA.
Ana BakhtiariTaskforce for Global Health, Atlanta, Georgia, USA.
Cristina JimenezSightsavers, Haywards Heath, UK.
Michael DejeneSightsavers, Addis Ababa, Ethiopia.
Anthony W SolomonDepartment of Control of Neglected Tropical Diseases, World Health Organization, Geneva, Switzerland.
Emma M Harding-EschClinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
Kamal H BinnawiSudan National Trachoma Control Programme, Khartoum, Sudan.
London School of Hygiene & Tropical Medicine · GBThe Task Force for Global Health · USSightsavers · GBWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionThe prevalence of trachomatous inflammation-follicular (TF) in 1-9-year-olds and of trachomatous trichiasis (TT) in ≥15-year-olds in four endemic evaluation units (EUs) of Darfur region, Sudan, was measured more than a year after the required single round of antibiotic mass drug administration (MDA).

methodsSurveys were conducted using highly standardised, World Health Organization-recommended methodologies. Individuals aged ≥1 year, resident in selected households, were chosen for the survey using a two-stage cluster sampling process. Consenting adults and children were examined for the signs TF and TT by graders trained to international standards. Prevalence of disease in key indicator groups was calculated and weighted to the underlying population structure.

resultsA mean of 1,415 (range: 1,253-1,611) children aged 1-9 years were examined in each EU. The age-adjusted prevalence of TF in 1-9-year-olds in each of the four surveyed EUs was <5%. A mean of 1,139 people aged ≥15 years (range: 1,080-1,201) were examined in each EU. The estimated age- and gender-adjusted prevalence of TT in ≥15-year-olds was <0.2% in all four EUs. In general, the proportion of households with access to improved WASH facilities was generally lower in this study than in corresponding baseline studies.

conclusionsNo further MDA should be conducted in these four EUs for the next 2 years, at which point they should be re-surveyed to determine whether the prevalence of TF in 1-9-year-olds has remained <5%. Active TT case-finding is also not indicated. Environmental improvement and promotion of facial cleanliness measures should continue to be implemented to prevent disease recrudescence.

Indexed as

TrachomaTrichiasisAdultAnti-Bacterial AgentsChildCross-Sectional StudiesHumansInfantMass Drug AdministrationPrevalenceSudanAnti-Bacterial AgentsDarfureliminationneglected tropical diseasesSudanTrachomatrichiasis

Identifiers

PMID34423732
PMCPMC10581671
OpenAlexW3194183485

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.