Evidence map›Paper›PMID 34423679›Full record

ArticleAmerican journal of physiology. Renal physiology2021

Mast cell function in prostate inflammation, fibrosis, and smooth muscle cell dysfunction.

Goutham Pattabiraman, Ashlee J Bell-Cohn, Stephen F Murphy, Daniel J Mazur, Anthony J Schaeffer, Praveen Thumbikat

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Mechanisms of prostatic inflammation-mediated male lower urinary tract symptoms.American journal of clinical and experimental urology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Goutham PattabiramanDepartment of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-5196-8279
Ashlee J Bell-CohnDepartment of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Stephen F MurphyDepartment of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Daniel J MazurDepartment of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Anthony J SchaefferDepartment of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Praveen ThumbikatDepartment of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.ORCID 0000-0002-5454-4172
Northwestern University · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Mast cells in male pelvic pain and lower urinary tract dysfunctionR01DK083609 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI THUMBIKAT, PRAVEEN · 2010 to 2020
$3.4M
Inflammatory Pathways in BPH/LUTSR01DK117906 · NIDDK · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI HAYWARD, SIMON W, THUMBIKAT, PRAVEEN · 2018 to 2021
$2.2M
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK083609HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK117906NCI NIH HHS P30 CA060553NIDDK NIH HHS R01 DK083609NIDDK NIH HHS R01 DK117906
6 · The paper itself

Abstract

Intraurethral inoculation of mice with uropathogenic

Indexed as

AnimalsAnti-Allergic AgentsCetirizineCromolyn SodiumEscherichia coliEscherichia coli InfectionsFibrosisHumansMaleMast CellsMiceMice, Inbred C57BLMyocytes, Smooth MuscleProstateProstatic DiseasesUrinationAnti-Allergic AgentsCetirizineCromolyn Sodiumfibrosisinflammationmast cellprostatesmooth muscle cell contraction

Identifiers

PMID34423679
PMCPMC8560406
OpenAlexW3194169242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.