ArticleJournal of the American Heart Association2021
Cardiovascular Health Trajectories and Elevated C-Reactive Protein: The CARDIA Study.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- The Association Between Pregnancy Complications and Long-term Maternal Cardiometabolic Health in the MIREC Cohort Study.The Journal of clinical endocrinology and metabolism · 2025Article
- Associations of early pregnancy high-sensitivity C-reactive protein levels with subsequent gestational diabetes: A Finnish gestational diabetes study.Diabetology & metabolic syndrome · 2025Article
- Cardiovascular Health Trajectories and Prevalent Metabolic Dysfunction-Associated Steatotic Liver Disease in Midlife: The CARDIA Study.Journal of the American Heart Association · 2025Article
- Unclosed wound: effect of childhood access to healthcare on cardiovascular health trajectories of Chinese older adults based on entropy balancing analysis.Frontiers in public health · 2025Article
- Synergistic effects of glucose tolerance and BMI on cardiovascular events and all-cause mortality in a healthy population: CA.ME.LI.A study 7 years follow-up.American journal of physiology. Endocrinology and metabolism · 2024Article
- Life's essential 8 and risk of subclinical atherosclerosis progression: a prospective cohort study.Journal of geriatric cardiology : JGC · 2024Article
- Article
- Molecular Biomarkers for Cardiometabolic Disease: Risk Assessment in Young Individuals.Circulation research · 2023Review
- Is there a cost to caring? Dispositional affective empathy interacts with depressive symptoms to predict higher C-reactive protein 8 years later.Biological psychology · 2023Article
- Estimation of Life's Essential 8 Score with Incomplete Data of Individual Metrics.medRxiv : the preprint server for health sciences · 2023Article
- Analysis of C-reactive protein from finger stick dried blood spot to predict high risk of cardiovascular disease.Scientific reports · 2023Article
- The 30-year cardiovascular risk trajectories and their independently associated factors in participants of a Brazilian cohort (CUME Study).Cadernos de saude publica · 2023Article
- Estimation of life's essential 8 score with incomplete data of individual metrics.Frontiers in cardiovascular medicine · 2023Article
- Article
- Role of C-reactive protein in disease progression, diagnosis and management.Discoveries (Craiova, Romania)Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Background The relationship between long-term cardiovascular health (CVH) patterns and elevated CRP (C-reactive protein) in late middle age has yet to be investigated. We aimed to assess this relationship. Methods and Results Individual CVH components were measured in 4405 Black and White men and women (aged 18-30 years at baseline) in the CARDIA (Coronary Artery Risk Development in Young Adults) study at 8 examinations over 25 years. CRP was measured at 4 examinations (years 7, 15, 20, and 25). Latent class modeling was used to identify individuals with similar trajectories in CVH from young adulthood to middle age. Multivariable Poisson regression models were used to assess the association between race-specific CVH trajectories and prevalence of elevated CRP levels (>3.0 mg/L) after 25 years of follow-up. Five distinct CVH trajectories were identified for each race. Lower and decreasing trajectories had higher prevalence of elevated CRP relative to the highest trajectory. Prevalence ratios for elevated CRP in lowest trajectory groups at year 25 were 2.58 (95% CI, 1.89-3.51) and 7.20 (95% CI, 5.09-10.18) among Black and White people, respectively. Prevalence ratios for chronically elevated CRP (elevated CRP at 3 or more of the examinations) in the lowest trajectory groups were 8.37 (95% CI, 4.37-16.00) and 15.89 (95% CI, 9.01-28.02) among Black and White people, respectively. Conclusions Lower and decreasing CVH trajectories are associated with higher prevalence of elevated CRP during the transition from young adulthood to middle age.
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