Evidence map›Paper›PMID 34423600›Full record

ArticleJournal of veterinary science2021

Metastasis prognostic factors and cancer stem cell-related transcription factors associated with metastasis induction in canine metastatic mammary gland tumors.

Saetbyul Kim, Eunyeong Bok, Sangyeob Lee, Hyeon-Jeong Lee, Yongho Choe, Na-Hyun Kim, Won-Jae Lee, Gyu-Jin Rho, Sung-Lim Lee

Abstract read
In one paragraph

Article in Journal of veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Canine Mammary Cancer: State of the Art and Future Perspectives.Animals : an open access journal from MDPI · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Saetbyul Kim *Department of Veterinary Obstetrics, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0001-8172-186X
Eunyeong Bok *Department of Veterinary Obstetrics, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0002-1045-9670
Sangyeob LeeDepartment of Veterinary Obstetrics, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0001-8024-1135
Hyeon-Jeong LeeDepartment of Veterinary Obstetrics, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0002-2154-239X
Yongho ChoeDepartment of Veterinary Obstetrics, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0003-0788-4745
Na-Hyun KimGyeongnam Department of Environment & Toxicology, Korea Institute of Toxicology, Munsan 52834, Korea.ORCID https://orcid.org/0000-0002-9518-1478
Won-Jae LeeDepartment of Veterinary Obstetrics, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea.ORCID https://orcid.org/0000-0003-1462-7798
Gyu-Jin RhoDepartment of Veterinary Obstetrics, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0002-6264-0017
Sung-Lim LeeDepartment of Veterinary Obstetrics, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea.ORCID https://orcid.org/0000-0002-1055-8097

Funding

National Research Foundation of Korea NRF-2021R1A2C1007054
6 · The paper itself

Abstract

backgroundCanine mammary gland tumor (MGT) is the most common cancer in aged female dogs. Although it's important to identify reliable metastasis or prognostic factors by evaluating related to cell division, adhesion, and cancer stem cell-related transcription factor (TF) in metastasis-induced canine MGT, but there are limited studies.

objectivesWe aimed to identify metastasis prognostic factors and cancer stem cell-TFs in canine MGTs.

methodsAge-matched female dogs diagnosed with MGT only were classified into metastatic and non-metastatic groups by histopathological staining of MGT tissues. The mRNA levels of cancer prognostic metastasis molecular factors (

resultsThe mRNA levels of

conclusionsConsistent expression patterns of all metastasis-related factors showing elevation in

Indexed as

Neoplasm MetastasisAnimalsDog DiseasesDogsFemaleMammary Neoplasms, AnimalNeoplastic Stem CellsPrognosisTranscription FactorsTranscription FactorsCaninemammary gland tumormetastasisprognostic molecular markersstem cell markers

Identifiers

PMID34423600
PMCPMC8460459

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.