Evidence map›Paper›PMID 34423412›Full record

ArticleApplied microbiology and biotechnology2021

Do initial concentration and activated sludge seasonality affect pharmaceutical biotransformation rate constants?

Tamara J H M van Bergen, Ana B Rios-Miguel, Tom M Nolte, Ad M J Ragas, Rosalie van Zelm, Martien Graumans, Paul T J Scheepers, Mike S M Jetten, A Jan Hendriks, Cornelia U Welte

Abstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tamara J H M van Bergen *Department of Environmental Science, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands. t.vanbergen@science.ru.nl.
Ana B Rios-Miguel *Department of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Tom M NolteDepartment of Environmental Science, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Ad M J RagasDepartment of Environmental Science, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Rosalie van ZelmDepartment of Environmental Science, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Martien GraumansRadboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Paul T J ScheepersRadboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Mike S M JettenDepartment of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
A Jan HendriksDepartment of Environmental Science, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands.
Cornelia U WelteDepartment of Microbiology, Institute for Water and Wetland Research, Radboud University, Nijmegen, The Netherlands. c.welte@science.ru.nl.ORCID http://orcid.org/0000-0002-1568-8878

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek 024.002.002Stichting voor de Technische Wetenschappen 15759
6 · The paper itself

Abstract

Pharmaceuticals find their way to the aquatic environment via wastewater treatment plants (WWTPs). Biotransformation plays an important role in mitigating environmental risks; however, a mechanistic understanding of involved processes is limited. The aim of this study was to evaluate potential relationships between first-order biotransformation rate constants (k

Indexed as

Pharmaceutical PreparationsWater Pollutants, ChemicalBiotransformationChromatography, LiquidRNA, Ribosomal, 16SSewageTandem Mass SpectrometryPharmaceutical PreparationsRNA, Ribosomal, 16SSewageWater Pollutants, ChemicalBacterial communityKineticsNitrificationOrganic micropollutantsSorptionWastewater treatment plants

Identifiers

PMID34423412
PMCPMC8403117

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.