Evidence map›Paper›PMID 34423331›Full record

ArticleLancet regional health. Americas2021

Clinical characteristics of the first and second COVID-19 waves in the Bronx, New York: A retrospective cohort study.

Wouter S Hoogenboom, Antoine Pham, Harnadar Anand, Roman Fleysher, Alexandra Buczek, Selvin Soby, Parsa Mirhaji, Judy Yee, Tim Q Duong

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

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  12. Experiences of U.S. frontline physicians during the COVID-19 pandemic: a qualitative study.Archives of public health = Archives belges de sante publique · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wouter S HoogenboomDepartment of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Antoine PhamDepartment of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Harnadar AnandDepartment of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Roman FleysherDepartment of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Alexandra BuczekDepartment of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Selvin SobyCenter for Health Data Innovations, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Parsa MirhajiCenter for Health Data Innovations, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Judy YeeDepartment of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.
Tim Q DuongDepartment of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited clinical patient data comparing the first and second waves of the coronavirus disease 2019 (COVID-19) in the United States and the effects of a COVID-19 resurgence on different age, racial and ethnic groups. We compared the first and second COVID-19 waves in the Bronx, New York, among a racially and ethnically diverse population.

methodsPatients in this retrospective cohort study were included if they had a laboratory-confirmed SARS-CoV-2 infection by a real-time PCR test of a nasopharyngeal swab specimen detected between March 11, 2020, and January 21, 2021. Main outcome measures were critical care, in-hospital acquired disease and death. Patient demographics, comorbidities, vitals, and laboratory values were also collected.

findingsA total of 122,983 individuals were tested for SARS-CoV-2 infection, of which 12,659 tested positive. The second wave was characterized by a younger demographic, fewer comorbidities, less extreme laboratory values at presentation, and lower risk of adverse outcomes, including in-hospital mortality (adj. OR = 0·23, 99·5% CI = 0·17 to 0·30), hospitalization (adj. OR = 0·65, 99·5% CI = 0·58 to 0·74), invasive mechanical ventilation (adj. OR = 0·70, 99·5% CI = 0·56 to 0·89), acute kidney injury (adj. OR = 0·62, 99·5% CI = 0·54 to 0·71), and length of stay (adj. OR = 0·71, 99·5% CI = 0·60 to 0·85), with Black and Hispanic patients demonstrating most improvement in clinical outcomes.

interpretationThe second COVID-19 wave in the Bronx exhibits improved clinical outcomes compared to the first wave across all age, racial, and ethnic groups, with minority groups showing more improvement, which is encouraging news in the battle against health disparities.

Indexed as

BronxCoronavirusCOVID-19EthnicityMortalityRaceResurgenceSARS-CoV-2

Identifiers

PMID34423331
PMCPMC8367084

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.